Issues
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Cover image
Cover Image
Confocal section of a Drosophila scrib tumor showing adhered hemocytes, labeled by He-Gal4-driven GFP expression (cyan). All nuclei stained with DAPI (red). See research article by Pastor-Pareja et al. on page 144. - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
RESEARCH HIGHLIGHT
EDITORIAL
COMMUNITY NEWS
A high-tech infusion for science
Alex Griekspoor’s PhD in cell biology led to an interesting and unexpected twist that resulted in a unique career in computer programming. Now he creates new computer technology using his blend of research knowledge and computer prowess. After bringing the science community programs like Papers and 4Peaks, Dr Griekspoor started his own software company, mekentosj.com and the future looks bright.
A MODEL FOR LIFE
The future of cancer therapy: an interview with Gerard Evan
Gerard Evan is a founding editor of DMM, whose work uncovered a crucial role for the tumor suppressor Myc in cellular apoptosis. Here, he talks about the future of cancer therapy and the responsibility of academic science in tackling these complex questions.
CLINICAL PUZZLE
SPECIAL ARTICLE
COMMENTARY
PERSPECTIVE
RESEARCH ARTICLE
RESEARCH REPORT
DMM Journal Meeting 2024: Pre-clinical Modelling of Human Genetic Disease and Therapy

Registration is now open for our 2024 Journal Meeting. Rapid advances in gene editing and genetic technologies have revolutionised our ability to model human genetic disease and provided new hope for gene therapies. At this Meeting, we will present the very latest advances in modelling human genetic disease.
A new call for papers is underway

Showcase your latest research in our upcoming special issue Translating Multiscale Research in Rare Disease, coordinated by DMM Editors Monica Justice, Karen Liu and Monkol Lek, and Guest Editor Kate Rauen. The deadline for submitting articles to the special issue is Monday 6 November 2023.
Moving towards heart success – Disease Models & Mechanisms Special Issue

DMM's most recent special issue compiles articles that aim to move heart failure to heart success by fundamentally addressing the roots of failure to identify curative strategies.
Crossroads in Virology

Our October Editorial written by Sumana Sanyal emphasises the urgency of a concerted effort in understanding virus–host interactions to inform the development of therapeutics and vaccines, helping to predict disease outcomes. Read the full Editorial here.
NOTCH signalling – a core regulator of bile duct disease?




In this Review, Anabel Martinez Lyons and Luke Boulter explore the concepts of NOTCH signalling reactivation in the biliary epithelium and how it is a reiterative and essential response to bile duct damage. Read the full Review Article here.