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Infectious disease biology

The COVID-19 pandemic and the spread of antimicrobial-resistant strains of major pathogens have renewed scientific and public interest in understanding infectious diseases and developing effective therapies to combat them. Although model systems have been crucial, this research faces ongoing challenges. This collection, launched to celebrate the DMM Journal Meeting ‘Infectious Diseases Through an Evolutionary Lens’, seeks contribute to the ongoing conversation between basic scientists, clinical researchers and clinicians. By highlighting rigorous, high-quality science in these areas, we hope to improve our understanding of infectious diseases and new treatment approaches. EM image of septin proteins building cages (red) to entrap bacteria (blue) that invade human cells, courtesy of Serge Mostowy (https://themostowylab.org/).

REVIEW

Exploring host–pathogen interactions in the Dictyostelium discoideum–Mycobacterium marinum infection model of tuberculosis

Sandra Guallar-Garrido; Thierry Soldati

22 July 2024

https://doi.org/10.1242/dmm.050698

RESEARCH ARTICLE

Contribution of Streptococcus pseudopneumoniae and Streptococcus salivarius to vocal fold mucosal integrity and function

Vlasta Lungova; Madhu Gowda; Jessica M. Fernandez; Stephanie Bartley; Anumitha Venkatraman; Federico E. Rey; Susan L. Thibeault

16 July 2024

https://doi.org/10.1242/dmm.050670

SPECIAL ARTICLE

Key considerations to improve the normalization, interpretation and reproducibility of morbidity data in mammalian models of viral disease

Jessica A. Belser; Troy J. Kieran; Zoë A. Mitchell; Xiangjie Sun; Kristin Mayfield; Terrence M. Tumpey; Jessica R. Spengler; Taronna R. Maines

05 March 2024

https://doi.org/10.1242/dmm.050511

RESOURCES & METHODS

A Zika virus protein expression screen in Drosophila to investigate targeted host pathways during development

Nichole Link; J. Michael Harnish; Brooke Hull; Shelley Gibson; Miranda Dietze; Uchechukwu E. Mgbike; Silvia Medina-Balcazar; Priya S. Shah; Shinya Yamamoto

28 February 2024

https://doi.org/10.1242/dmm.050297

RESEARCH ARTICLE

Postnatal Zika virus infection leads to morphological and cellular alterations within the neurogenic niche

Jéssica C. C. G. Ferreira; Raissa R. Christoff; Tailene Rabello; Raiane O. Ferreira; Carolina Batista; Pedro Junior Pinheiro Mourão; Átila D. Rossi; Luiza M. Higa; Maria Bellio; Amilcar Tanuri; Patricia P. Garcez

28 February 2024

https://doi.org/10.1242/dmm.050375

REVIEW

How metals fuel fungal virulence, yet promote anti-fungal immunity

Alanoud Alselami; Rebecca A. Drummond

31 October 2023

https://doi.org/10.1242/dmm.050393

EDITORIAL

Crossroads in virology: current challenges and future perspectives in the age of emerging viruses

Sumana Sanyal

20 September 2023

https://doi.org/10.1242/dmm.050476

REVIEW

Zika virus infection histories in brain development

Bruna L. M. Marcelino; Brendha L. dos Santos; Jhulimar G. Doerl; Samantha F. Cavalcante; Sara N. Maia; Nivia M. R. Arrais; Andrea Zin; Selma M. B. Jeronimo; Claudio Queiroz; Cecilia Hedin-Pereira; Eduardo B. Sequerra

17 July 2023

https://doi.org/10.1242/dmm.050005

REVIEW

Understanding the neurological implications of acute and long COVID using brain organoids

Laura García-González; Andrea Martí-Sarrias; Maria C. Puertas; Ángel Bayón-Gil; Patricia Resa-Infante; Javier Martinez-Picado; Arcadi Navarro; Sandra Acosta

17 July 2023

https://doi.org/10.1242/dmm.050049

RESOURCE ARTICLE

An automated microscopy workflow to study Shigella –neutrophil interactions and antibiotic efficacy in vivo

Arthur Lensen; Margarida C. Gomes; Ana Teresa López-Jiménez; Serge Mostowy

10 May 2023

https://doi.org/10.1242/dmm.049908

RESOURCE ARTICLE

An arginase 2 promoter transgenic line illuminates immune cell polarisation in zebrafish

Ffion R. Hammond; Amy Lewis; Zoë C. Speirs; Holly E. Anderson; Tamara Sipka; Lewis G. Williams; Mai Nguyen-Chi; Annemarie H. Meijer; Geert F. Wiegertjes; Philip M. Elks

03 May 2023

https://doi.org/10.1242/dmm.049966

REVIEW

Evolution and immunopathology of chikungunya virus informs therapeutic development

Filipa Henderson Sousa; Amalina Ghaisani Komarudin; Fern Findlay-Greene; Anom Bowolaksono; R. Tedjo Sasmono; Craig Stevens; Peter G. Barlow

04 April 2023

https://doi.org/10.1242/dmm.049804

A MODEL FOR LIFE

Redefining tuberculosis: an interview with Lalita Ramakrishnan

Lalita Ramakrishnan

23 March 2023

https://doi.org/10.1242/dmm.050189

RESEARCH ARTICLE

Loss of Shp1 impairs myeloid cell function and causes lethal inflammation in zebrafish larvae

Maaike Allers; Petra A. Bakker; Jelmer Hoeksma; Herman P. Spaink; Jeroen den Hertog

30 January 2023

https://doi.org/10.1242/dmm.049715

RESEARCH ARTICLE | REVIEW COMMONS TRANSFER

A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein

Sabrina Yahiya; Charlie N. Saunders; Sarah Hassan; Ursula Straschil; Oliver J. Fischer; Ainoa Rueda-Zubiaurre; Silvia Haase; Gema Vizcay-Barrena; Mufuliat Toyin Famodimu; Sarah Jordan; Michael J. Delves; Edward W. Tate; Anna Barnard; Matthew J. Fuchter; Jake Baum

30 January 2023

https://doi.org/10.1242/dmm.049950

RESEARCH ARTICLE

Piglet cardiopulmonary bypass induces intestinal dysbiosis and barrier dysfunction associated with systemic inflammation

Jeffrey D. Salomon; Haowen Qiu; Dan Feng; Jacob Owens; Ludmila Khailova; Suzanne Osorio Lujan; John Iguidbashian; Yashpal S. Chhonker; Daryl J. Murry; Jean-Jack Riethoven; Merry L. Lindsey; Amar B. Singh; Jesse A. Davidson

12 January 2023

https://doi.org/10.1242/dmm.049742

A MODEL FOR LIFE

Pasteur's legacy persists: an interview with Pascale Cossart

Pascale Cossart

12 December 2022

https://doi.org/10.1242/dmm.050009

EDITORIAL

Louis Pasteur continues to shape the future of microbiology

Serge Mostowy

12 December 2022

https://doi.org/10.1242/dmm.050011

RESEARCH ARTICLE

Comparison of the pathogenesis of SARS-CoV-2 infection in K18-hACE2 mouse and Syrian golden hamster models

Haengdueng Jeong; Youn Woo Lee; In Ho Park; Hyuna Noh; Sung-Hee Kim; Jiseon Kim; Donghun Jeon; Hui Jeong Jang; Jooyeon Oh; Dain On; Chanyang Uhm; Kyungrae Cho; Heeju Oh; Suhyeon Yoon; Jung Seon Seo; Jeong Jin Kim; Sang-Hyuk Seok; Yu Jin Lee; Seung-Min Hong; Se-Hee An; Seo Yeon Kim; Young Been Kim; Ji-Yeon Hwang; Hyo-Jung Lee; Hong Bin Kim; Dae Gwin Jeong; Daesub Song; Manki Song; Man-Seong Park; Kang-Seuk Choi; Jun Won Park; Jun-Young Seo; Jun-Won Yun; Jeon-Soo Shin; Ho-Young Lee; Ki Taek Nam; Je Kyung Seong

11 November 2022

https://doi.org/10.1242/dmm.049632

RESOURCE ARTICLE

An adherent-invasive Escherichia coli -colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease

Adeline Sivignon; Mélissa Chervy; Caroline Chevarin; Elia Ragot; Elisabeth Billard; Jérémy Denizot; Nicolas Barnich

24 October 2022

https://doi.org/10.1242/dmm.049707

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Showcase your latest research on our upcoming Special Issue: Infectious Disease: Evolution, Mechanisms and Global Health. This issue will be coordinated by DMM Editors Sumana Sanyal and David Tobin alongside Guest Editors Judi Allen and Russell Vance. The deadline for submitting articles to this Special Issue has been extended to Monday 24 February 2025.

Biologists @ 100 - join us in Liverpool in March 2025

We are excited to invite you to a unique scientific conference, celebrating the 100-year anniversary of The Company of Biologists, and bringing together our different communities. The conference will incorporate a DMM programme on antimicrobial resistance on 26 March 2025. Find out more and register to join us in March 2025 in Liverpool, UK. The deadline for abstract submission and early-bird registration is 17 January 2025.

It's about time: the heterochronic background for the 2024 Nobel Prize in Physiology or Medicine

In this Editorial, Bruce Wightman writes about the groundwork laid by investigating the timing of developmental events in nematodes which led to the 2024 Nobel Prize in Physiology or Medicine.

Read & Publish Open Access publishing: what authors say

We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.

Infectious disease biology

Call for Papers – Infectious Disease: Evolution, Mechanisms and Global Health

Biologists @ 100 - join us in Liverpool in March 2025

It's about time: the heterochronic background for the 2024 Nobel Prize in Physiology or Medicine

Read & Publish Open Access publishing: what authors say

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