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Drosophila as a Disease Model
Drosophila melanogaster has been a popular model organism since the early 20th century, when Thomas H. Morgan first used the organism in the study of heredity. The experimental tractability of fruit flies and their similarity to humans have placed them at the forefront of research into human development and disease. This collection from DMM features reviews, research, resources, interviews and other articles, including specially commissioned content from our 2016 special issue Spotlight on Drosophila: Translational Impact, which was guest edited by Norbert Perrimon and Nancy Bonini.

REVIEW
Anna M. Salazar; Ricardo Aparicio; Rebecca I. Clark; Michael Rera; David W. Walker
04 May 2023
Doi:
10.1242/dmm.049969
RESEARCH ARTICLE
Mark A. Hanson; Bruno Lemaitre
26 April 2023
Doi:
10.1242/dmm.049965
RESEARCH ARTICLE
Sarah J. Gignac; Katja R. MacCharles; Katherine Fu; Kywana Bonaparte; Gamze Akarsu; Thalia W. Barrett; Esther M. Verheyen; Joy M. Richman
13 April 2023
Doi:
10.1242/dmm.049844
RESEARCH ARTICLE
John E. La Marca; Robert W. Ely; Sarah T. Diepstraten; Peter Burke; Gemma L. Kelly; Patrick O. Humbert; Helena E. Richardson
03 April 2023
Doi:
10.1242/dmm.049769
RESEARCH ARTICLE
Lídia Faria; Sara Canato; Tito T. Jesus; Margarida Gonçalves; Patrícia S. Guerreiro; Carla S. Lopes; Isabel Meireles; Eurico Morais-de-Sá; Joana Paredes; Florence Janody
21 February 2023
Doi:
10.1242/dmm.049652
RESEARCH ARTICLE | REVIEW COMMONS TRANSFER
Travis D. Carney; Rucha Y. Hebalkar; Evgeniia Edeleva; Ibrahim Ömer Çiçek; Halyna R. Shcherbata
31 January 2023
Doi:
10.1242/dmm.049862
RESEARCH ARTICLE
Marco Travaglio; Filippos Michopoulos; Yizhou Yu; Rebeka Popovic; Edmund Foster; Muireann Coen; L. Miguel Martins
25 January 2023
Doi:
10.1242/dmm.049727
RESEARCH ARTICLE
Xiao Li; Meng Zhang; Mengmeng Liu; Tzu-Hao Liu; Rajitha-Udakara-Sampath Hemba-Waduge; Jun-Yuan Ji
14 November 2022
Doi:
10.1242/dmm.049650
RESEARCH ARTICLE
Deena Damschroder; Rubén Zapata-Pérez; Kristin Richardson; Frédéric M. Vaz; Riekelt H. Houtkooper; Robert Wessells
05 October 2022
Doi:
10.1242/dmm.049279
RESEARCH ARTICLE
Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival
Kathrin Pfeifer; Georg Wolfstetter; Vimala Anthonydhason; Tafheem Masudi; Badrul Arefin; Mats Bemark; Patricia Mendoza-Garcia; Ruth H. Palmer
16 August 2022
Doi:
10.1242/dmm.049591
RESEARCH ARTICLE
Pavitra Prakash; Arpit Kumar Pradhan; Vasu Sheeba
28 June 2022
Doi:
10.1242/dmm.049447
RESEARCH ARTICLE
Marcus T. Glittenberg; Ilias Kounatidis; Magda Atilano; Petros Ligoxygakis
09 May 2022
Doi:
10.1242/dmm.049218
RESEARCH ARTICLE | REVIEW COMMONS TRANSFER
Rujuta Deshpande; Byoungchun Lee; Yuemeng Qiao; Savraj S. Grewal
09 May 2022
Doi:
10.1242/dmm.049551
RESEARCH ARTICLE
Ryan R. Myers; Jonatan Sanchez-Garcia; Daniel C. Leving; Richard G. Melvin; Pedro Fernandez-Funez
03 May 2022
Doi:
10.1242/dmm.049184
REVIEW
Andre Medina; Karen Bellec; Sofia Polcowñuk; Julia B. Cordero
28 March 2022
Doi:
10.1242/dmm.049332
REVIEW
Ying Liu; Pedro Saavedra; Norbert Perrimon
23 March 2022
Doi:
10.1242/dmm.049298
RESEARCH ARTICLE
Deepika Vasudevan; Hidetaka Katow; Huai-Wei Huang; Grace Tang; Hyung Don Ryoo
16 March 2022
Doi:
10.1242/dmm.049119
RESEARCH ARTICLE
Ajai J. Pulianmackal; Kiriaki Kanakousaki; Kerry Flegel; Olga G. Grushko; Ella Gourley; Emily Rozich; Laura A. Buttitta
16 March 2022
Doi:
10.1242/dmm.049234
RESEARCH ARTICLE
Xueya Cao; Marta Rojas; José Carlos Pastor-Pareja
26 January 2022
Doi:
10.1242/dmm.049160
RESEARCH ARTICLE
Xiaoming Feng; Xizhen Hong; Qiuxia Fan; Liting Chen; Jing Li; Juan Deng; Siqiao Gong; Fan Fan Hou; Fujian Zhang
21 September 2021
Doi:
10.1242/dmm.047464