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Advanced In Vitro Models: A New Dimension In Translational Research Modelling

Organoids and bioengineered three-dimensional culture systems offer more accurate representation of the cellular microenvironment than traditional monolayer culture. They can be genetically modified to phenocopy development and disease, test therapeutic interventions and screen drugs. This collection features a selection of articles on the use of organoid, three-dimensional tissue culture and organ-on-chip models in translational research.

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Sara Y. Brucker; Thomas Hentrich; Julia M. Schulze-Hentrich; Martin Pietzsch; Noel Wajngarten; Anjali Ralhan Singh; Katharina Rall; André Koch
Doi: 10.1242/dmm.049379
Conor J. McGrath; Edgaras Laveckis; Andrew Bell; Emmanuelle Crost; Nathalie Juge; Stephanie Schüller
Doi: 10.1242/dmm.049365
Christy B. M. Tulen; Ying Wang; Daan Beentjes; Phyllis J. J. Jessen; Dennis K. Ninaber; Niki L. Reynaert; Frederik-Jan van Schooten; Antoon Opperhuizen; Pieter S. Hiemstra; Alexander H. V. Remels
Doi: 10.1242/dmm.049247
Zhao-Feng Li; Lei Cui; Mi-Mi Jin; Dong-Yan Hu; Xiao-Gang Hou; Shu-Shu Liu; Xiong Zhang; Jian-Hong Zhu
Doi: 10.1242/dmm.049125
Oleksandr Nychyk; Gabriel L. Galea; Matteo Molè; Dawn Savery; Nicholas D. E. Greene; Philip Stanier; Andrew J. Copp
Doi: 10.1242/dmm.049194
Aaron R. Shoemaker; Ian E. Jones; Kira D. Jeffris; Gina Gabrielli; Alyssa G. Togliatti; Rajeswari Pichika; Eric Martin; Evangelos Kiskinis; Colin K. Franz; John D. Finan
Doi: 10.1242/dmm.048916
Manuel J. Del Rey; Carolina Meroño; Cristina Municio; Alicia Usategui; María Mittelbrunn; Inés García-Consuegra; Gabriel Criado; José L. Pablos
Doi: 10.1242/dmm.048995
Jelte van der Vaart; Mart M. Lamers; Bart L. Haagmans; Hans Clevers
Doi: 10.1242/dmm.049060
Marine Besnard; Francine Padonou; Nathan Provin; Matthieu Giraud; Carole Guillonneau
Doi: 10.1242/dmm.046359
Katie Lloyd; Stamatia Papoutsopoulou; Emily Smith; Philip Stegmaier; Francois Bergey; Lorna Morris; Madeleine Kittner; Hazel England; Dave Spiller; Mike H. R. White; Carrie A. Duckworth; Barry J. Campbell; Vladimir Poroikov; Vitor A. P. Martins dos Santos; Alexander Kel; Werner Muller; D. Mark Pritchard; Chris Probert; Michael D. Burkitt; The SysmedIBD Consortium
Doi: 10.1242/dmm.044040
Shohei Yoshimoto; Junko Yoshizumi; Hiromasa Anzai; Koichiro Morishita; Kazuhiko Okamura; Akimitsu Hiraki; Shuichi Hashimoto
Doi: 10.1242/dmm.045054
Alec R. Nickolls; Michelle M. Lee; Kristen Zukosky; Barbara S. Mallon; Carsten G. Bönnemann
Doi: 10.1242/dmm.042986
Mark L. Kovler; Chhinder P. Sodhi; David J. Hackam
Doi: 10.1242/dmm.044388
Madeline A. Lancaster; Meritxell Huch
Doi: 10.1242/dmm.039347
Emily J. Jones; Zoe J. Matthews; Lejla Gul; Padhmanand Sudhakar; Agatha Treveil; Devina Divekar; Jasmine Buck; Tomasz Wrzesinski; Matthew Jefferson; Stuart D. Armstrong; Lindsay J. Hall; Alastair J. M. Watson; Simon R. Carding; Wilfried Haerty; Federica Di Palma; Ulrike Mayer; Penny P. Powell; Isabelle Hautefort; Tom Wileman; Tamas Korcsmaros
Doi: 10.1242/dmm.037069
Carmen Hurtado del Pozo; Elena Garreta; Juan Carlos Izpisúa Belmonte; Nuria Montserrat
Doi: 10.1242/dmm.035048
Kenta Kawasaki; Masayuki Fujii; Toshiro Sato
Doi: 10.1242/dmm.029595
Qi Xu; Sanna Junttila; Andreas Scherer; Khem Raj Giri; Oona Kivelä; Ilya Skovorodkin; Juha Röning; Susan E. Quaggin; Hans-Peter Marti; Jingdong Shan; Anatoly Samoylenko; Seppo J. Vainio
Doi: 10.1242/dmm.028332
Michael D. Burkitt; Carrie A. Duckworth; Jonathan M. Williams; D. Mark Pritchard
Doi: 10.1242/dmm.027649
Sean R. Moore; Jill Pruszka; Jefferson Vallance; Eitaro Aihara; Toru Matsuura; Marshall H. Montrose; Noah F. Shroyer; Christian I. Hong
Doi: 10.1242/dmm.014399
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