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C. elegans as a Disease Model

The nematode worm Caenorhabditis elegans is one of the best-characterised multicellular organisms on Earth. Its significant degree of homology and defined cell lineage, genome and life cycle render this small animal ideal for modelling diseases associated with neuronal and metabolic dysfunction, ageing and host-pathogen interactions. DMM presents a collection of articles showcasing how C. elegans can bridge basic and translational research into human disease.

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Lexis D. Kepler; Troy A. McDiarmid; Catharine H. Rankin
Doi: 10.1242/dmm.049359
Caitlin S. Latimer; Jade G. Stair; Joshua C. Hincks; Heather N. Currey; Thomas D. Bird; C. Dirk Keene; Brian C. Kraemer; Nicole F. Liachko
Doi: 10.1242/dmm.049323
Carmen Martínez-Fernández; Milana Bergamino; Alfonso Schiavi; David Brena; Natascia Ventura; Sebastian Honnen; Alberto Villanueva; Ernest Nadal; Julián Cerón
Doi: 10.1242/dmm.049161
Ineke Dhondt; Clara Verschuuren; Aleksandra Zečić; Tim Loier; Bart P. Braeckman; Winnok H. De Vos
Doi: 10.1242/dmm.049169
Peter A. Kropp; Rosemary Bauer; Isabella Zafra; Carina Graham; Andy Golden
Doi: 10.1242/dmm.049010
Marte Molenaars; Bauke V. Schomakers; Hyung L. Elfrink; Arwen W. Gao; Martin A. T. Vervaart; Mia L. Pras-Raves; Angela C. Luyf; Reuben L. Smith; Mark G. Sterken; Jan E. Kammenga; Antoine H. C. van Kampen; Georges E. Janssens; Frédéric M. Vaz; Michel van Weeghel; Riekelt H. Houtkooper
Doi: 10.1242/dmm.047746
Karen I. Lange; Sofia Tsiropoulou; Katarzyna Kucharska; Oliver E. Blacque
Doi: 10.1242/dmm.046631
James J. Doyle; Celine Vrancx; Claudia Maios; Audrey Labarre; Shunmoogum A. Patten; J. Alex Parker
Doi: 10.1242/dmm.041350
Kim A. Caldwell; Corey W. Willicott; Guy A. Caldwell
Doi: 10.1242/dmm.046110
Éva Saskői; Zoltán Hujber; Gábor Nyírő; István Likó; Barbara Mátyási; Gábor Petővári; Katalin Mészáros; Attila L. Kovács; László Patthy; Shreyas Supekar; Hao Fan; Gergely Sváb; László Tretter; Arunabh Sarkar; Aamir Nazir; Anna Sebestyén; Attila Patócs; Anil Mehta; Krisztina Takács-Vellai
Doi: 10.1242/dmm.044925
Sangeetha Iyer; Feba S. Sam; Nina DiPrimio; Graeme Preston; Jan Verheijen; Kausalya Murthy; Zachary Parton; Hillary Tsang; Jessica Lao; Eva Morava; Ethan O. Perlstein
Doi: 10.1242/dmm.040584
Sangeetha Iyer; Joshua D. Mast; Hillary Tsang; Tamy P. Rodriguez; Nina DiPrimio; Madeleine Prangley; Feba S. Sam; Zachary Parton; Ethan O. Perlstein
Doi: 10.1242/dmm.040576
Edward F. Griffin; Samuel E. Scopel; Cayman A. Stephen; Adam C. Holzhauer; Madeline A. Vaji; Ryan A. Tuckey; Laura A. Berkowitz; Kim A. Caldwell; Guy A. Caldwell
Doi: 10.1242/dmm.037218
Jennifer E. Hewitt; Amelia K. Pollard; Leila Lesanpezeshki; Colleen S. Deane; Christopher J. Gaffney; Timothy Etheridge; Nathaniel J. Szewczyk; Siva A. Vanapalli
Doi: 10.1242/dmm.036137
Troy A. McDiarmid; Vinci Au; Aaron D. Loewen; Joseph Liang; Kota Mizumoto; Donald G. Moerman; Catharine H. Rankin
Doi: 10.1242/dmm.036517
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