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C. elegans as a Disease Model

The nematode worm Caenorhabditis elegans is one of the best-characterised multicellular organisms on Earth. Its significant degree of homology and defined cell lineage, genome and life cycle render this small animal ideal for modelling diseases associated with neuronal and metabolic dysfunction, ageing and host-pathogen interactions. DMM presents a collection of articles showcasing how C. elegans can bridge basic and translational research into human disease.

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RESEARCH ARTICLE
Karen I. Lange; Sofia Tsiropoulou; Katarzyna Kucharska; Oliver E. Blacque
Doi: 10.1242/dmm.046631
RESEARCH ARTICLE
James J. Doyle; Celine Vrancx; Claudia Maios; Audrey Labarre; Shunmoogum A. Patten; J. Alex Parker
Doi: 10.1242/dmm.041350
AT A GLANCE
Kim A. Caldwell; Corey W. Willicott; Guy A. Caldwell
Doi: 10.1242/dmm.046110
RESEARCH ARTICLE
Éva Saskői; Zoltán Hujber; Gábor Nyírő; István Likó; Barbara Mátyási; Gábor Petővári; Katalin Mészáros; Attila L. Kovács; László Patthy; Shreyas Supekar; Hao Fan; Gergely Sváb; László Tretter; Arunabh Sarkar; Aamir Nazir; Anna Sebestyén; Attila Patócs; Anil Mehta; Krisztina Takács-Vellai
Doi: 10.1242/dmm.044925
RESEARCH ARTICLE
Sangeetha Iyer; Feba S. Sam; Nina DiPrimio; Graeme Preston; Jan Verheijen; Kausalya Murthy; Zachary Parton; Hillary Tsang; Jessica Lao; Eva Morava; Ethan O. Perlstein
Doi: 10.1242/dmm.040584
RESEARCH ARTICLE
Sangeetha Iyer; Joshua D. Mast; Hillary Tsang; Tamy P. Rodriguez; Nina DiPrimio; Madeleine Prangley; Feba S. Sam; Zachary Parton; Ethan O. Perlstein
Doi: 10.1242/dmm.040576
RESEARCH ARTICLE
Edward F. Griffin; Samuel E. Scopel; Cayman A. Stephen; Adam C. Holzhauer; Madeline A. Vaji; Ryan A. Tuckey; Laura A. Berkowitz; Kim A. Caldwell; Guy A. Caldwell
Doi: 10.1242/dmm.037218
RESEARCH ARTICLE
Jennifer E. Hewitt; Amelia K. Pollard; Leila Lesanpezeshki; Colleen S. Deane; Christopher J. Gaffney; Timothy Etheridge; Nathaniel J. Szewczyk; Siva A. Vanapalli
Doi: 10.1242/dmm.036137
RESOURCE ARTICLE
Troy A. McDiarmid; Vinci Au; Aaron D. Loewen; Joseph Liang; Kota Mizumoto; Donald G. Moerman; Catharine H. Rankin
Doi: 10.1242/dmm.036517
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