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Neurodegeneration: from Models to Mechanisms to Therapies

A growing aging population means that age-dependent neurodegenerative disorders are affecting increasing numbers of people. Model systems have proven to be excellent tools for studying neurodegenerative processes, facilitating drug discovery in this area. DMM features reviews, research, resources, interviews and other articles, including specially commissioned content from our 2017 special issue Neurodegeneration: from Models to Mechanisms to Therapies, which was guest edited by Aaron Gitler and James Shorter.

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SPECIAL ARTICLE
Charlotte M. Fare; James Shorter
Doi: 10.1242/dmm.048983
RESEARCH ARTICLE
Fréderike W. Riemslagh; Esmay C. van der Toorn; Rob F. M. Verhagen; Alex Maas; Laurens W. J. Bosman; Renate K. Hukema; Rob Willemsen
Doi: 10.1242/dmm.044842
RESEARCH ARTICLE
Rachel Atkinson; Jacqueline Leung; James Bender; Matthew Kirkcaldie; James Vickers; Anna King
Doi: 10.1242/dmm.047548
RESEARCH ARTICLE
Sarah D. Neuman; Erica L. Terry; Jane E. Selegue; Amy T. Cavanagh; Arash Bashirullah
Doi: 10.1242/dmm.046417
RESEARCH ARTICLE
Ian Adams; Tao Yang; Frank M. Longo; David M. Katz
Doi: 10.1242/dmm.044685
AT A GLANCE
Kim A. Caldwell; Corey W. Willicott; Guy A. Caldwell
Doi: 10.1242/dmm.046110
RESEARCH ARTICLE
Gideon L. Hughes; Michael A. Lones; Matthew Bedder; Peter D. Currie; Stephen L. Smith; Mary Elizabeth Pownall
Doi: 10.1242/dmm.045815
RESEARCH ARTICLE
S. Schuster; E. Heuten; A. Velic; J. Admard; M. Synofzik; S. Ossowski; B. Macek; S. Hauser; L. Schöls
Doi: 10.1242/dmm.045096
REVIEW
Julia Gamache; Young Yun; Ornit Chiba-Falek
Doi: 10.1242/dmm.045211
RESEARCH ARTICLE
Molly Mepyans; Livia Andrzejczuk; Jahree Sosa; Sierra Smith; Shawn Herron; Samantha DeRosa; Susan A. Slaugenhaupt; Albert Misko; Yulia Grishchuk; Kirill Kiselyov
Doi: 10.1242/dmm.044230
RESEARCH ARTICLE
Daniel Fil; Balu K. Chacko; Robbie Conley; Xiaosen Ouyang; Jianhua Zhang; Victor M. Darley-Usmar; Aamir R. Zuberi; Cathleen M. Lutz; Marek Napierala; Jill S. Napierala
Doi: 10.1242/dmm.045229
RESEARCH ARTICLE
Valeria Valsecchi; Marina Boido; Francesca Montarolo; Michela Guglielmotto; Simona Perga; Serena Martire; Santina Cutrupi; Andrea Iannello; Nadia Gionchiglia; Elena Signorino; Andrea Calvo; Giuseppe Fuda; Adriano Chiò; Antonio Bertolotto; Alessandro Vercelli
Doi: 10.1242/dmm.043513
REVIEW
John R. P. Knight; Gavin Garland; Tuija Pöyry; Emma Mead; Nikola Vlahov; Aristeidis Sfakianos; Stefano Grosso; Fabio De-Lima-Hedayioglu; Giovanna R. Mallucci; Tobias von der Haar; C. Mark Smales; Owen J. Sansom; Anne E. Willis
Doi: 10.1242/dmm.043208
RESEARCH ARTICLE
Jorge L. Rodriguez-Gil; Dawn E. Watkins-Chow; Laura L. Baxter; Gene Elliot; Ursula L. Harper; Stephen M. Wincovitch; Julia C. Wedel; Arturo A. Incao; Mylene Huebecker; Frederick J. Boehm; William S. Garver; Forbes D. Porter; Karl W. Broman; Frances M. Platt; William J. Pavan
Doi: 10.1242/dmm.042614
RESOURCE ARTICLE
Eric M. Clark; Hannah J. T. Nonarath; Jonathan R. Bostrom; Brian A. Link
Doi: 10.1242/dmm.041426
RESEARCH ARTICLE
Cathryn L. Ugalde; Sarah J. Annesley; Shane E. Gordon; Katelyn Mroczek; Matthew A. Perugini; Victoria A. Lawson; Paul R. Fisher; David I. Finkelstein; Andrew F. Hill
Doi: 10.1242/dmm.040899
RESEARCH ARTICLE
Monika Baxa; Bozena Levinska; Monika Skrivankova; Matous Pokorny; Jana Juhasova; Jiri Klima; Jiri Klempir; Jan Motlı́k; Stefan Juhas; Zdenka Ellederova
Doi: 10.1242/dmm.041293
RESEARCH ARTICLE
Taras Ardan; Monika Baxa; Božena Levinská; Miroslava Sedláčková; The Duong Nguyen; Jiří Klíma; Štefan Juhás; Jana Juhásová; Petra Šmatlíková; Petra Vochozková; Jan Motlík; Zdenka Ellederová
Doi: 10.1242/dmm.041319
RESEARCH ARTICLE
Urmas Roostalu; Casper B. G. Salinas; Ditte D. Thorbek; Jacob L. Skytte; Katrine Fabricius; Pernille Barkholt; Linu M. John; Vanessa Isabell Jurtz; Lotte Bjerre Knudsen; Jacob Jelsing; Niels Vrang; Henrik H. Hansen; Jacob Hecksher-Sørensen
Doi: 10.1242/dmm.042200
RESEARCH ARTICLE
Eleftheria Pervolaraki; Stephen P. Hall; Denise Foresteire; Takashi Saito; Takaomi C. Saido; Miles A. Whittington; Colin Lever; James Dachtler
Doi: 10.1242/dmm.040550
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