Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availabilityby Sullivan et al.

Cancer metabolism: what can we learn from analysing metabolites in tumour infiltrating fluid rather than in blood plasma?

Selected by Maria Rafaeva. Read the preLight here

Mechanical Stretch Kills Transformed Cancer Cellsby Tijore et al.

Forcefully aiming at cancer cells.

Selected by Vibha Singh. Read the preLight here

A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heartby Honkoop et al.

Heart regeneration: Cardiomyocytes need to undergo a metabolic switch in order to re-enter the cell cycle.

Selected by Andreas van Impel. Read the preLight here

A schizophrenia risk gene, NRGN, bidirectionally modulates synaptic plasticity via regulating the neuronal phosphoproteomeby Hongik Hwang

Hwang et al. show neurogranin regulates CaM-Ca2+ levels and phosphatase activity in the post-synaptic compartment and influences synaptic plasticity.

Selected by Laura McCormick. Read the preLight here

A conserved MFS orchestrates a subset of O-glycosylation to facilitate macrophage dissemination and tissue invasionby Valoskova et al.

Minerva instructs Drosophila embryonic macrophages to push the boundaries of tissue invasion by initiating a developmentally controlled program of glycosylation.

Selected by Giuliana Clemente. Read the preLight here

Applications of Machine Learning in Decision Analysis for Dose Management for Dofetilideby Levy et al.

AND

Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non-Small Cell Lung Cancer

by Schneider et al.

Where dosing dreams are born: Developments in drug toxicity modelling and reinforcement learning in optimising drug dosing regimens.

Selected by Zhang-He Goh. Read the preLight here

Bacteriophage resistance alters antibiotic mediated intestinal expansion of enterococciby Chatterjee et al.

Resistance is futile: Phage therapy used with antibiotics to combat enterococci in a dysbiotic microbiota.

Selected by Yasmin Lau. Read the preLight here

Tracking the popularity and outcomes of all bioRxiv preprintsby Abdill & Blekhman

What makes preprints popular? preLighters respond to a meta-analysis of bioRxiv preprints.

Read the preLight here