... for growth and patterning of the Drosophila wing. The Drosophila BMP gene, gbb-60A , exhibits a requirement in wing morphogenesis distinct from that shown previously for dpp , a well-characterized Drosophila BMP member. gbb-60A mutants exhibit a loss of pattern elements from the wing, particularly those...

... on each wing surface. Finally, overexpression of an α PS subunit throughout the wing leads to a dominant wing blister phenotype, and the critical period for this phenotype is the beginning of pupariation. These data indicate that integrin requirements in wing morphogenesis can be separated into early...

... of Biologists 1995 PS integrin multiple edematous wings mew muscle attachment wing morphogenesis eye morphogenesis Integrins are the major class of cell surface receptors for extracellular matrix components (reviewed by Hynes, 1992 ). The basic structure of integrins is strongly...

...-associated microtubules during Drosophila wing morphogenesis . Eur. J. Cell Biol. 41 , 279 – 289 . Waddington , C. H. ( 1941 ). The genetic control of wing development in Drosophila . J. Genet. 41 , 75 – 139 . Wessendorf , L. H. V. , Wehrli , M. , DiAntonio...

... to four basal junctions per pair of connected cells ( Fig. 4B ). During metamorphosis, wing morphogenesis depends on a series of four key steps: 1. Apposition (the basal surfaces of dorsal and ventral epithelia come together). 2. Adhesion (junctions form between the apposed basal surfaces). 3...