... 10 2015 15 12 2015 First, there has been duplication of genes encoding several components of the Hh pathway in vertebrates. This includes not only the Hh gene itself, of which there are three paralogues in birds and mammals (Desert, Indian and Sonic), two of which (Indian and Sonic...

...Tyler Square; Marek Romášek; David Jandzik; Maria V. Cattell; Michael Klymkowsky; Daniel M. Medeiros Lamprey is one of only two living jawless vertebrates, a group that includes the first vertebrates. Comparisons between lamprey and jawed vertebrates have yielded important insights into the origin...

...Bea Christen; Alexandre Miguel Cavaco Rodrigues; Monserrat Barragán Monasterio; Carme Fabregat Roig; Juan Carlos Izpisua Belmonte Bone morphogenetic protein (Bmp) signalling has been implicated in setting up dorsoventral patterning of the vertebrate limb and in its outgrowth. Here, we present...

... polarity complex and the Fat/Dachsous system. Components of both pathways also function in vertebrates and are implicated in diverse morphogenetic processes, some of which self-evidently involve planar polarisation and some of which do not. Here, we review the molecular mechanisms and cellular consequences...

... of the force-generating muscles to the solid support of the organism: the skeleton in vertebrates and the exoskeleton in invertebrates. Here, we discuss recent findings that illuminate musculoskeletal assembly in the vertebrate embryo, findings that emphasize the reciprocal interactions between the forming...

...Susanne Theis; Ketan Patel; Petr Valasek; Anthony Otto; Qin Pu; Itamar Harel; Eldad Tzahor; Shahragim Tajbakhsh; Bodo Christ; Ruijin Huang In vertebrates, body musculature originates from somites, whereas head muscles originate from the cranial mesoderm. Neck muscles are located in the transition...

... chondrogenesis and, acting as a member of Meinox-Pbc-Hox trimers, it plays an essential role in hindbrain development. * Author for correspondence (e-mail: [email protected] ) 27 10 2003 © 2004. 2004 Vertebrate Zebrafish Hox Pbx Meis Prep Rhombomere Segmentation...

...Florencia Cavodeassi; Juan Modolell; José Luis Gómez-Skarmeta The Iroquois (Iro) family of genes are found in nematodes, insects and vertebrates. They usually occur in one or two genomic clusters of three genes each and encode transcriptional controllers that posses a characteristic homeodomain...

...James M. McClintock; Robin Carlson; Devon M. Mann; Victoria E. Prince As a result of a whole genome duplication event in the lineage leading to teleosts, the zebrafish has seven clusters of Hox patterning genes, rather than four, as described for tetrapod vertebrates. To investigate...

.... ‡Author for correspondence (e-mail: [email protected] ) 12 4 2001 © 2001. 2001 Left-right axis formation Vertebrate Embryogenesis Patterning Chick PKI is a peptide of 76 amino acids that was originally isolated from rabbit skeletal muscle by its ability to inhibit...

...Ilya Ruvinsky; Jeremy J. Gibson-Brown ABSTRACT Two sets of paired appendages are a characteristic feature of the body plan of jawed vertebrates. While the fossil record provides a good morphological description of limb evolution, the molecular mechanisms involved in this process are only now...

...Véronique Dubreuil; Marie-Rose Hirsch; Alexandre Pattyn; Jean-François Brunet; Christo Goridis ABSTRACT In the vertebrate neural tube, cell cycle exit of neuronal progenitors is accompanied by the expression of transcription factors that define their generic and sub-type specific properties...

... for correspondence (e-mail: [email protected] ) 21 04 2000 13 06 2000 © 2000 by Company of Biologists 2000 Growth control Angiosperm Vertebrate Drosophila Why are mice smaller than men? Why are pea pods smaller than pumpkins? Why are arms shorter than legs? What controls...

...Sylke Winkler; Felix Loosli; Thorsten Henrich; Yuko Wakamatsu; Joachim Wittbrodt ABSTRACT In early vertebrate eye development, the retinal anlage is specified in the anterior neuroectoderm. During neurulation, the optic vesicles evaginate from the lateral wall of the prosencephalon. Here we...

...Kristin D. Patterson; Thomas A. Drysdale; Paul A. Krieg ABSTRACT The spleen is a vertebrate organ that has both hematopoietic and immunologic function. The embryonic origins of the spleen are obscure, with most studies describing the earliest rudiment of the spleen as a condensation of mesodermal...

...Robert L. Chow; Curtis R. Altmann; Richard A. Lang; Ali Hemmati-Brivanlou ABSTRACT We report here that misexpression of the transcription factor Pax6 in the vertebrate Xenopus laevis leads to the formation of differentiated ectopic eyes. Multiple molecular markers indicated the presence of mature...

...Detlev Arendt; Katharina Nübler-Jung ABSTRACT It is widely held that the insect and vertebrate CNS evolved independently. This view is now challenged by the concept of dorsoventral axis inversion, which holds that ventral in insects corresponds to dorsal in vertebrates. Here, insect and vertebrate...

...Concepción Rodriguez-Esteban; John W. R. Schwabe; Jennifer De La Peña; Diego E. Rincon-Limas; Jorge Magallón; Juan Botas; Juan Carlos Izpisúa Belmonte ABSTRACT apterous specifies dorsal cell fate and directs outgrowth of the wing during Drosophila wing development. Here we show that, in vertebrates...

...Mark Sefton; Silvia Sánchez; M. Angela Nieto ABSTRACT The members of the Snail family of zinc-finger transcription factors have been implicated in the formation of distinct tissues within the developing vertebrate and invertebrate embryo. Two members of this family have been described in higher...

[email protected] ) 18 12 1997 04 02 1998 © 1998 by Company of Biologists 1998 Fgf Neural retina Optic vesicle Eye development Retrovirus Vertebrate Development of the vertebrate eye depends on the coordinated interaction of three distinct tissues: neuroepithelium, overlying...