...: Abrogation of Hippo signaling in mouse Müllerian duct mesenchyme cells causes them to adopt the myofibroblast fate, resulting in reproductive tract developmental defects and sterility. Lats1/2 Uterus Müllerian duct Mesenchyme Myofibroblast Cell fate Mouse The Müllerian ducts...

... and continuation of pregnancy then requires a viable embryo, a receptive uterus and effective molecular communication between the two. But how do the blastocysts survive and remain viable during this period of time, which can be up to a year in some cases? And what are the signals that bring it out of suspended...

... in combination with 3D analysis to identify and quantify dynamic changes to the luminal structure of murine uterus in preparation for implantation. When applied to mouse mutants with known implantation defects, this method detected striking peri-implantation abnormalities in uterine morphology that cannot...

... uterus, and an accumulation of fibrillar-like structures observed by electron microscopy in Vangl2 Lp mutant epithelium suggests that mislocalization of Scrb1 in mutants alters the composition of the apical face of the epithelium. Heterozygous and homozygous Vangl2 Lp mutant postnatal tissues exhibit...

... the axes of the embryo and the uterus at the beginning of gastrulation, a perplexing phenomenon discovered two decades ago. * Author for correspondence (e-mail: [email protected] ) 3 4 2007 © 2007. 2007 It was discovered almost two decades ago that the AP axis of the mouse embryo...

...-mail: [email protected] ) 14 11 2006 © 2007. 2007 Dprp ( Dtprp ) Decidua Pregnancy Uterus Null mutation Adaptations to hypoxia Mouse The establishment of pregnancy requires maternal adjustments. Hemochorial placentation, which occurs in both primates and rodents, results...

[email protected] ) * Present address: Laboratoire de Biologie de la Différenciation,Université Paris 7, 2, place Jussieu – case 7136, 75 005 Paris,France. 22 1 2004 © 2004. 2004 Wnt Uterus Mouse DES Glands The mammalian female reproductive tract (FRT) is derived from...

... failed to express p63, remained columnar and persisted into adulthood as adenosis. * Author for correspondence (e-mail: [email protected] ) 15 12 2003 © 2004. 2004 Columnar-squamous transformation Müllerian duct Endocrine disruptor Uterus Estrogen receptor α...

..., metanephros and fetal gonads. Using, a Lim1 lacZ knock-in allele in mice, we identified a previously unreported urogenital tissue for Lim1 expression, the epithelium of the developing Müllerian duct that gives rise to the oviduct, uterus and upper region of the vagina of the female reproductive tract. Lim1...

... whether HB-EGF plays any role in implantation in hamsters, we examined the expression, regulation and signaling of HB-EGF in the hamster embryo and uterus during the periimplantation period. We demonstrate that both the blastocyst and uterus express HB-EGF during implantation. Hegfl is expressed solely...

... that a short delay in the initial attachment reaction creates a ripple effect propagating developmental anomalies during the subsequent course of pregnancy. *Author for correspondence (e-mail: [email protected] ) 26 3 2002 © 2002. 2002 cPLA 2 α implantation uterus embryo pregnancy...

..., and (3) ERα is also necessary for interstitial glandular cell development. Our data also indicate that ERβ exerts some function in ERαKO uterus and vagina. ERαβKO granulosa cells localized within degenerating follicles transform into cells displaying junctions that are unique to testicular Sertoli cells...

...Xuemei Zhao; Wen-ge Ma; Sanjoy K. Das; Sudhansu K. Dey; Bibhash C. Paria ABSTRACT The process of implantation is a ‘two-way’ interaction between the blastocyst and uterus. It has long been suspected that histamine is an important mediator in embryo-uterine interactions during implantation, but its...

...Anna P. Newman; Gwen Z. Acton; Erika Hartwieg; H. Robert Horvitz; Paul W. Sternberg The Caenorhabditis elegans hermaphrodite egg-laying system comprises several tissues, including the uterus and vulva. lin-11 encodes a LIM domain transcription factor needed for certain vulval precursor cells...

...- and motorneurons, in epithelial cells of the uterus and in the excretory system. Loss of lim-6 function affects late events in the differentiation of two classes of GABAergic motorneurons which control rhythmic enteric muscle contraction. lim-6 is required to specify the correct axon morphology of these neurons...

...Gail V. Benson; Hyunjung Lim; B. C. Paria; Ichiro Satokata; Sudhansu K. Dey; Richard L. Maas ABSTRACT The establishment of a receptive uterine environment is critical for embryonic survival and implantation. One gene that is expressed in the uterus during the peri-implantation period in mice...

... 02115, USA † Present address: Department of Pharmacy, State University of New York, Buffalo, NY 14214, USA 21 03 1996 © 1996 by Company of Biologists 1996 metalloproteinase TIMP mouse implantation trophoblast decidua apoptosis transgenic embryo uterus...

... properly into the scrotum and, likely as a result, spermatogenesis is perturbed. * Author for correspondence 30 01 1995 © 1995 by Company of Biologists 1995 homeobox gene antisense transcripts limb development spermatogenesis uterus mouse The 38 mammalian Hox genes...

... possible interactions between the uterine HB-EGF and blastocyst EGF-R very early in the process of implantation, earlier than any other embryo-uterine interactions defined to date at the molecular level. 31 01 1994 © 1994 by Company of Biologists 1994 HB-EGF EGF-R blastocyst uterus...

...JoAnne Julian; Ruth Chiquet-Ehrismann; Harold P. Erickson; Daniel D. Carson ABSTRACT Expression of tenascin, an extracellular matrix protein associated with morphogenetic events and altered states of cellular adhesion, was examined in mouse uterus during the peri-implantation period. A uniform low...