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Keywords: transgenic mice
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Journal Articles
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Reproductive biology
Journal: Development
Development (2023) 150 (21): dev201907.
Published: 27 October 2023
... acid Sertoli cell-only Spermatogenesis Transgenic mice References Al-Khadairi , G. and Decock , J. ( 2019 ). Cancer testis antigens and immunotherapy: Where do we stand in the targeting of PRAME? Cancers (Basel) 11 , 1 - 14 . 10.3390/cancers11070984 Anderson...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (22): 3879–3891.
Published: 15 November 2015
... Transgenic mice The proper functioning of neural networks depends crucially on their precise topography being correctly established and maintained. A crucial regulator of neural network development is neural activity, which has been shown to be vital for many aspects of brain development ( Zhang...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (18): 3301–3305.
Published: 15 September 2012
... in this paper but wish to disclose that the establishment and germline transmission of haploid mouse ESCs has been submitted as part of a patent application. 26 6 2012 © 2012. Haploid embryonic stem cells Germline Transgenic mice Parthenogenesis Haploid embryonic stem...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2005) 132 (15): 3549–3559.
Published: 1 August 2005
... depends on DM cells in a non-cell-autonomous fashion. * Author for correspondence (e-mail: [email protected] ) 23 5 2005 ©2005. 2005 Roof plate Fate map Genetic ablation Bmp Gdf7 Transgenic mice Cre recombinase Diphtheria toxin Mouse The choroid plexus (CP) produces...
Journal Articles
Journal: Development
Development (2005) 132 (8): 1855–1862.
Published: 15 April 2005
... EC1V 9EL, UK 2 2 2005 ©2005. 2005 Astrocytes Retina Blood vessels PDGF-A Oxygen Transgenic mice Retinal astrocytes are believed to be responsible for controlling development of the retinal vasculature in mammals. Astrocytes emerge from the optic nerve head around birth...
Journal Articles
Journal: Development
Development (2004) 131 (14): 3469–3479.
Published: 15 July 2004
... in human breast tumors. However, the role of MTA1 in tumorigenesis in a physiologically relevant animal system remains unknown. To reveal the role of MTA1 in mammary gland development, transgenic mice expressing MTA1 under the control of the mouse mammary tumor virus promoter long terminal repeat were...
Journal Articles
Journal: Development
Development (2003) 130 (19): 4709–4718.
Published: 1 October 2003
[email protected] ) * Present address: Department of Developmental Neurobiology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA 18 6 2003 © 2003. 2003 Oligodendrocytes TK ablation system Transgenic mice Cerebellum Development Cerebellar...
Journal Articles
Journal: Development
Development (2002) 129 (13): 3045–3054.
Published: 1 July 2002
... signalling and provide insights into a genetic hierarchy involving Gli 3, Emx 2 and Bmp and Wnt genes in the control of dorsal telencephalic development. *Author for correspondence (e-mail: [email protected] ) 12 4 2002 © 2002. 2002 Transgenic mice Gli 3 Wnt Bmp...
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (12): 2373–2384.
Published: 15 June 2001
... and Cdk4 activity, while Msx1 has minimal effects on cellular proliferation. Transgenic mice that express Msx1 under the control of the mouse mammary tumor virus long terminal repeat (MMTV LTR) display impaired differentiation of the mammary epithelium during pregnancy, which is accompanied by elevated...
Journal Articles
Journal: Development
Development (2001) 128 (9): 1617–1627.
Published: 1 May 2001
... demonstrated to be necessary for endogenous initiation of fiber cell differentiation. To test this possibility, we have generated transgenic mice with ocular expression of secreted self- dimerizing versions of FGFR1 (FR1) and FGFR3 (FR3). Expression of FR3, but not FR1, leads to an expansion of proliferating...
Journal Articles
Journal: Development
Development (2001) 128 (7): 1119–1126.
Published: 1 April 2001
... to maximize developmental competence of oocytes. * Author for correspondence (e-mail: [email protected] ) 11 01 2001 13 03 2001 © 2001 by Company of Biologists 2001 Zona pellucida Fertilization Embryonic stem cells Sperm-egg interactions Transgenic mice Folliculogenesis Pre...
Journal Articles
Journal: Development
Development (2000) 127 (20): 4455–4467.
Published: 15 October 2000
... purification was carried out as described by Manson et al. (1997) . YAC integrity was verified after each step of the purification process by PFGE and the concentration of the YAC DNA was estimated on a mini-gel using as a standard a DNA mass ladder (Gibco Life Technologies). Transgenic mice were generated...
Journal Articles
Journal: Development
Development (2000) 127 (17): 3829–3838.
Published: 1 September 2000
... transgenic mice. We are grateful to our colleagues in the laboratory for discussions, to T. Jessell for the anti-Chx10 antibody, to A. Joyner for anti-Engrailed 1 antibody and to R. H. Holmgren for polyclonal anti-β-gal antibody and fluorescent secondary antibodies. This work was supported by a research...
Journal Articles
Journal: Development
Development (2000) 127 (11): 2421–2432.
Published: 1 June 2000
...Meei-Hua Lin; Cornelia Leimeister; Manfred Gessler; Raphael Kopan ABSTRACT Little is known about the mechanisms underlying the generation of various cell types in the hair follicle. To investigate the role of the Notch pathway in this process, transgenic mice were generated in which an active form...
Journal Articles
Journal: Development
Development (2000) 127 (8): 1671–1679.
Published: 15 April 2000
... conditional reporter (R26R) Tooth formation Transgenic mice Wnt1 promoter The vertebrate neural crest is a pluripotent cell population derived from the lateral ridges of the neural plate during early stages of embryogenesis. Neural crest cells disperse from the dorsal surface of the neural tube...
Journal Articles
Journal: Development
Development (1999) 126 (20): 4441–4453.
Published: 15 October 1999
... virus was used to overexpress the human LEF1 gene in a human bronchial xenograft model of regenerative gland development in the adult airway. In a second model, the LEF1 gene was ectopically overexpressed under the direction of the proximal airway-specific CC10 promoter in transgenic mice. In both...