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Development (2009) 136 (22): 3821–3830.
Published: 15 November 2009
... germline is established by this time. Experiments where the sex of the soma was altered relative to that of the germline (by manipulating transformer ) reveal a dominant role for the soma in regulating initial germline sexual identity. Germ cells largely take on the sex of the surrounding soma, although...
Includes: Supplementary data
Development (2002) 129 (15): 3715–3725.
Published: 01 August 2002
...Attilio Pane; Marco Salvemini; Pasquale Delli Bovi; Catello Polito; Giuseppe Saccone The medfly Ceratitis capitata contains a gene ( Cctra ) with structural and functional homology to the Drosophila melanogaster sex-determining gene transformer ( tra ) . Similar to tra in Drosophila , Cctra is...
Development (2001) 128 (21): 4189–4201.
Published: 01 November 2001
...Clemens Kiecker; Christof Niehrs Anteroposterior (AP) patterning of the vertebrate neural plate is initiated during gastrulation and is regulated by Spemann’s organizer and its derivatives. The prevailing model for AP patterning predicts a caudally increasing gradient of a ‘transformer’ which...