... events underlying the eye-to-wing transdetermination described by Hadorn in 1968 reveal the roles of Pax6 and PcG proteins. Drosophila Eye Wing Pax6 Polycomb Antennapedia Teashirt Transdetermination National Eye Institute 10.13039/100000053 R01 EY014863 During...

...Ansgar Klebes; Anne Sustar; Katherina Kechris; Hao Li; Gerold Schubiger; Thomas B. Kornberg Drosophila imaginal disc cells can switch fates by transdetermining from one determined state to another. We analyzed the expression profiles of cells induced by ectopic Wingless expression to transdetermine...

... tissue is transformed not only into head cuticle but also into a variety of inappropriate structures. * Author for correspondence (e-mail: [email protected] ) 15 8 2002 ©2002. 2002 Drosophila Wingless Axin Eyes absent Sine oculis Dachshund Eye Transdetermination...

... Vestigial (Vg) and transdetermine to wing cells. Here we show that ectopic wg expression non-cell-autonomously induces Vg expression in leg discs and that activated Armadillo, a cytosolic transducer of the Wg signal, cell-autonomously induces Vg expression in leg discs, indicating that this Vg expression...

...Laura A. Johnston; Gerold Schubiger ABSTRACT We have expressed the segment polarity gene wingless ( wg ) ectopically in imaginal discs to examine its regulation of both ventral patterning and transdetermination. By experimentally manipulating the amount of Wg protein, we show that different...

... state through extra cell divisions but also for the ability to transdetermine, or switch to the determined state of a different disc. An understanding of transdetermination at a molecular level will provide further insight into the requirements for maintaining cell determination. We find that ectopic...