... precursor cells, our findings are fundamental for understanding precursor cell fate acquisition in other systems. Bristle lineage E(spl) genes Neural cell commitment Notch pathway Snail factors Transcription repression Centre National de la Recherche Scientifique 10.13039/501100004794...

...Vaniyambadi V. Sridhar; Anandkumar Surendrarao; Zhongchi Liu The transcriptional repression of key regulatory genes is crucial for plant and animal development. Previously, we identified and isolated two Arabidopsis transcription co-repressors LEUNIG ( LUG ) and SEUSS ( SEU ) that function together...

... abolishes Boz-dependent repression of bmp2b in the early blastula. Thus, Boz directly represses bmp2b by binding to control elements in the bmp2b locus. We propose that early transcriptional repression of bmp2b by Boz is one of the first steps toward formation of a stable organizer, whereas the later-acting...

... transcriptional repression. These three WT1 binding sites were also able to repress transcription, in a WT1-dependent manner, when inserted between a heterologous promoter and the reporter gene. The data indicate that Pax-2 is a likely target gene for WT1 and suggest a direct link, at the level of transcriptional...