... such as cytochrome C ( Wei et al., 2001 ). This in turn activates caspase 9 and subsequently the effector caspases. Apoptosis is responsible for tissue remodelling and regulating cell number in a range of tissues and organs during development ( Fuchs and Steller, 2011 ) and much of this occurs through the intrinsic...

.../978-1-4615-5399-1_83 Lang , R. A. and Bishop , M. J. ( 1993 ). Macrophages are required for cell death and tissue remodeling in the developing mouse eye . Cell 74 , 453 – 462 . 10.1016/0092-8674(93)80047-I Lang , R. A. , Lustig , M. , Francois , F...

... apoptosis vascular regression macrophage tissue remodelling tissue regression rat capillary regression Programmed capillary regression is a frequent occurrence in development. Despite the prevalence of this event, and the potential therapeutic value of an understanding of its mechanism...

... of Biologists 1994 development tissue remodelling tissue regression macrophage apoptosis Tissue regression is central to the development of species dis- tributed throughout the animal kingdom ( Glucksman, 1951 ; Saunders, 1966 ; Saunders and Fallon, 1967 ; Ellis et al., 1991b ; Ucker...

... development in normal (+/+ or +/op) mice In muscle and tendon, macrophages occur in regions of tissue remodeling, for example in areas of osteoinsertion and generally they are spindle-shaped with the major axis parallel to the fibers of both muscle and tendon. Macrophages of the dermis are generally...

... tissue remodelling adherens junctions cell adhesion molecules Early morphogenesis proceeds in part by means of successive reorganizations of tissue sheets via processes such as cell migrations, mesenchyme condensations into epithelia, foldings and dissociations of epithelia and separations...

... and functions of the matrix during neural crest cell migration, (ii) Type III collagen is apparently not required for tissue remodelling and cell migration during early embryogenesis, (iii) Type IV collagen and laminin are important components of the basal surface of epithelia and their distribution...