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Keywords: tissue organisation
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Journal Articles
Journal:
Development
Development (1990) 110 (4): 1001–1020.
Published: 1 December 1990
... and maturation leads us to formulate a spiral model of cell and tissue organisation . This concept is illustrated for the intestinal epithelium. It is concluded that the small intestinal crypts contain 4–16 actual stem cells in steady state but up to 30–40 potential stem cells (clonogenic cells) which may take...