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Keywords: tfap2a
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Journal Articles
Journal: Development
Development (2020) 147 (23): dev191973.
Published: 14 December 2020
... lineage assignment in the developing zebrafish pronephros by repressing Tfap2a activity. During renal ontogeny, expression of these factors colocalized with tfap2a in distal tubule precursors. kctd15a/b loss primed nephron cells to adopt distal fates by driving slc12a1 , kcnj1a.1 and stc1 expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (13): dev172387.
Published: 10 July 2019
... with discrete physiological identities. Here, from a forward genetic screen using zebrafish, we report the discovery that transcription factor AP-2 alpha ( tfap2a ) coordinates a gene regulatory network that activates the terminal differentiation program of distal segments in the pronephros. We found...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (12): 1987–1994.
Published: 15 June 2009
...Brigitte L. Arduini; Kevin M. Bosse; Paul D. Henion The neural crest generates multiple cell types during embryogenesis but the mechanisms regulating neural crest cell diversification are incompletely understood. Previous studies using mutant zebrafish indicated that foxd3 and tfap2a function early...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (7): 1279–1289.
Published: 1 April 2007
...Ting Luo; Yanhua Xu; Trevor L. Hoffman; Tailin Zhang; Thomas Schilling; Thomas D. Sargent Inca (induced in neural crest by AP2) is a novel protein discovered in a microarray screen for genes that are upregulated in Xenopus embryos by the transcriptional activator protein Tfap2a. It has...
Journal Articles
Journal: Development
Development (2004) 131 (7): 1463–1477.
Published: 1 April 2004
... of the tfap2a gene that abolishes the last exon encoding the crucial protein dimerization and DNA-binding domains. Neural crest induction and specification are not hindered in mob m610 mutant embryos, as revealed by normal expression of early neural crest specific genes such as snail2 , foxd3 and sox10...