... of F-class Fox proteins results in distal jaw truncations and absent midline cartilages and teeth. We show that Fox proteins are required for Sox9a to promote chondrogenic gene expression. Fox proteins are sufficient in neural crest-derived cells for cartilage development, and neural crest-specific...

...Paul T. Sharpe Mammalian teeth harbour mesenchymal stem cells (MSCs), which contribute to tooth growth and repair. These dental MSCs possess many in vitro features of bone marrow-derived MSCs, including clonogenicity, expression of certain markers, and following stimulation, differentiation...

...Jukka Jernvall; Irma Thesleff Teeth are found in almost all vertebrates, and they therefore provide a general paradigm for the study of epithelial organ development and evolution. Here, we review the developmental mechanisms underlying changes in tooth complexity and tooth renewal during evolution...

... exhibited hypercalcemia, hypophosphatemia and increased serum PTH, the volumes of teeth and of dental alveolar bone were decreased dramatically, whereas the ratio of the area of predentin to total dentin and the number and surface of osteoblasts in dental alveolar bone were increased significantly...

... whisker follicles teeth morphogenesis Bone morphogenetic protein-2A (BMP-2A) is a member of the transforming growth factor β (TGF β) gene family. More specifically, it belongs to the subgroup which includes the Drosophila decapentaplegic (dpp), Xenopus Vg-1 , murine Vgr-1 , and the BMP-2b...