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Keywords: tbx-35
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Journal Articles
Journal: Development
Development (2009) 136 (16): 2735–2746.
Published: 15 August 2009
... mutation in the T-box factor gene tbx-35 , a target of the MED-1 and MED-2 divergent GATA factors, was previously found to result in a profound decrease in the production of MS-derived tissues, although the tbx-35(-) embryonic arrest phenotype was variable. We report here that the NK-2 class homeobox gene...
Journal Articles
Journal: Development
Development (2006) 133 (16): 3097–3106.
Published: 15 August 2006
... of the pharynx. We have previously shown that MS is specified by the activity of the divergent MED-1,2 GATA factors. We report that the MED-1,2 target gene tbx-35 , which encodes a T-box transcription factor, specifies the MS fate. Embryos homozygous for a putative tbx-35 -null mutation fail to generate MS...