..., distribution and reproduction in any medium provided that the original work is properly attributed. Summary: The mangrove killifish, a self-fertilizing vertebrate model, allows rapid identification of the mutated genes noto and msgn1 from mutant strains and their genetic roles in tail bud...

... medicine. Axis elongation Gastrulation Neuromesodermal progenitors Primitive streak Tail bud Pluripotent stem cells Lineage specification in the early vertebrate embryo is initiated during gastrulation (see Glossary, Box 1), which involves the formation of the three germ layers...

... of the epithelial component of the BF remains unknown. The BF arises in the tail bud, caudal to the cloaca and in close association with the cloacal membrane, where the anal invagination (anal sinus) of ectoderm and the caudal endodermal wall of the cloaca are juxtaposed. Serial semi-thin sections of the tail bud...

... populations formed during gastrulation. To follow these populations over extended periods, we used cells from GFP-positive transgenic chick embryos as a source for donor tissue in grafting experiments. We determined that resident progenitor cell populations are localised in the chicken tail bud. One...

... embryogenesis, and exhibit defects in neural tube closure and in the development of the tail bud and pharyngeal arches. However, the mutant receptor is able to drive Fgfr1 functions during gastrulation and somitogenesis, and drives normal MAPK responses to Fgf. These findings indicate that Fgfr1 uses distinct...

...Suzan Abu-Abed; Pascal Dollé; Daniel Metzger; Caroline Wood; Glenn MacLean; Pierre Chambon; Martin Petkovich We have previously reported that the retinoic acid (RA) catabolizing enzyme CYP26A1 plays an important role in protecting tail bud tissues from inappropriate exposure to RA generated...

...Noemí Cambray; Valerie Wilson Elongation of the mouse anteroposterior axis depends on a small population of progenitors initially located in the primitive streak and later in the tail bud. Gene expression and lineage tracing have shown that there are many features common to these progenitor...

...Brahim Nait-Oumesmar; Barbara Stecca; Girish Fatterpekar; Thomas Naidich; Joshua Corbin; Robert A. Lazzarini Brief ectopic expression of Gcm1 in mouse embryonic tail bud profoundly affects the development of the nervous system. All mice from 5 independently derived transgenic lines exhibited either...

... is to regulate BMP activity. * Authors for correspondence (e-mail: [email protected] ; [email protected]) 16 02 2000 18 04 2000 © 2000 by Company of Biologists 2000 Noggin Secondary body formation Somitogenesis Tail bud Mesenchyme Ventral Ectodermal Ridge VER...

... Metalloprotease Pattern formation Tail Tail bud BMP chordin Dorsoventral Bone morphogenetic proteins (Bmps) and their signaling pathways are essential in the development of numerous tissues in vertebrates (reviewed in Hogan, 1996). One of the earliest developmental processes involving Bmp...

... μm long, while the epidermis of the tail is drawn from a much larger area. The fate map shows that much of the final tail is not formed from the tail bud itself, but by a displacement of trunk axial tissue relative to the proctodaeum. A specification map is also produced by culturing parts...

.... In zebrafish embryos, transcripts of wnt[a] are confined to the dorsal diencephalon, the dorsal midbrain, the rhombic lips and the dorsal portions of the spinal cord. wnt[b] is expressed in the tail bud and at considerably lower levels in the mesoderm of the head. wnt[c] transcripts are present within...

...Patrick P. L. Tam; Seong-Seng Tan ABSTRACT The developmental potency of cells isolated from the primitive streak and the tail bud of 8.5- to 13.5-day-old mouse embryos was examined by analyzing the pattern of tissue colonization after transplanting these cells to the primitive streak of 8.5-day...