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Keywords: spitz
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Journal Articles
Journal: Development
Development (2014) 141 (21): 4110–4114.
Published: 1 November 2014
... in development could be largely replaced by expression of any TGF-α ligand, including spitz ( spi ), in the endogenous vn pattern. vn mutants die as white undifferentiated pupae, but the rescued individuals showed global differentiation of adult body parts. Spi is more potent than Vn, and the best morphological...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (3): 563–570.
Published: 1 February 2004
... in the nucleus. In contrast, the mechanisms by which autocrine effects are regulated in the ligand-producing cell are unclear. In the Drosophila eye, Egfr signaling, induced by the Spitz ligand, is required for differentiation of all photoreceptors except for R8, the primary source of Spitz. R8 differentiation...
Journal Articles
Journal: Development
Development (2003) 130 (22): 5401–5412.
Published: 15 November 2003
... Patterning Ommatidial rotation Adhesion Epidermal growth factor receptor spitz keren scabrous nemo roulette argos Development of complex organisms requires tissues to undergo significant morphogenesis and remodelling. One example of such a process occurs in the Drosophila eye...
Journal Articles
Journal: Development
Development (2002) 129 (8): 1975–1982.
Published: 15 April 2002
... this response specificity. We have analysed the specification of bract cells in Drosophila legs. We observed that mechanosensory bristles induced bract fate in neighbouring epidermal cells, and that the RAS/MAPK pathway mediated this induction. We have identified Spitz and EGFr as the ligand and the receptor...