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Keywords: sox10
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (23): dev201133.
Published: 5 December 2022
... nuclear receptors as intrinsic activators of the ectomesenchyme program: zebrafish nr2f5 single and nr2f2;nr2f5 double mutants show marked delays in upregulation of ectomesenchyme genes, such as dlx2a , prrx1a , prrx1b , sox9a , twist1a and fli1a , and in downregulation of sox10 , which is normally...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (2): dev195339.
Published: 26 January 2021
...% of the enteric neurons and ∼90% of the Sox10-positive ENCDCs therein at 7 dpa were generated through proliferation. Thus, ENS regeneration involves proliferation, entrance and neurogenesis of ENCDCs. This is the first report regarding the regeneration process of the zebrafish ENS. Our findings provide a basis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1464–1474.
Published: 1 May 2016
... that the original work is properly attributed. Summary: Regeneration of spinal motor neurons following mechanical lesion or genetic ablation occurs at the expense of oligodendrogenesis and is promoted by the innate immune system. Dopamine Macrophage Microglia Nitroreductase Hb9 Olig2 Sox10...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (18): 3188–3197.
Published: 15 September 2015
... pathways, and exposure of the cells to pertinent growth factors led to the expression of the Schwann cell markers SOX10, KROX20 (EGR2), p75NTR (NGFR), MBP and S100B by day 4 in virtually all cells, and maturation was completed by 2 weeks of differentiation. Gene expression profiling demonstrated expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (13): 2691–2701.
Published: 1 July 2014
... the expression of Sox10 to promote the formation of secretory acinar lobes in the lacrimal gland. Sox9 and FGF signaling were required for the expression of cartilage-associated extracellular matrix components during early stage lacrimal gland development. Fgfr2 deletion in the ocular surface epithelium reduced...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (11): 2289–2298.
Published: 1 June 2013
... ( kenneth.campbell@cchmc.org ) Competing interests statement The authors declare no competing financial interests. 4 4 2013 © 2013. Published by The Company of Biologists Ltd 2013 Cell-fate specification Oligodendrocyte precursor cell Olig2 Pdgfrα Sox10 Telencephalon Mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (9): 1691–1699.
Published: 1 May 2012
.... We demonstrate temporal manipulation of Gal4 transgene expression in only primary motoneurons and not secondary motoneurons, heretofore impossible with conventional transgenic approaches. In another example, we follow and analyze neural crest cells that regained sox10 function after deactivation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (17): 3689–3698.
Published: 1 September 2011
...Paola Betancur; Tatjana Sauka-Spengler; Marianne Bronner The otic placode, a specialized region of ectoderm, gives rise to components of the inner ear and shares many characteristics with the neural crest, including expression of the key transcription factor Sox10. Here, we show that in avian...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (15): 2623–2632.
Published: 1 August 2009
..., as the speed of CNC cells was indistinguishable from that of wild-type counterparts. We determined that the failure of CNC cells to migrate away from the neural rod correlated with the enhanced expression of two transcription factors, foxd3 and sox10 . These transcription factors have many functions in CNC...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (21): 3555–3565.
Published: 1 November 2008
... in enteric neural crest cells (ENCCs) resulting from premature neurogenesis. We found that Sox10 expression, which is normally maintained in ENCC progenitors, was decreased in Pofut1 -null ENCCs. By contrast,the number of ENCCs that expressed Mash1, a potent repressor of Sox10, was increased in the Pofut1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (12): 2151–2160.
Published: 15 June 2008
... system. In the embryonic mouse pancreas, we found Phox2b expressed briefly together with Sox10 along the epithelial-mesenchymal border at E12.5 in cells derived from the neural crest. Downregulation of Phox2b shortly thereafter was dependent upon Nkx2.2 expressed in the adjacent pancreatic epithelium...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (23): 4255–4263.
Published: 1 December 2007
.... * Author for correspondence (e-mail: niehrs@dkfz-heidelberg.de ) 4 9 2007 © 2007. 2007 Dkk Kremen LRP6 Mesd Slug Sox10 Wnt Xenopus The canonical Wnt/β-catenin signaling cascade is an evolutionarily conserved and ancient pathway playing major roles during animal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (21): 3805–3814.
Published: 1 November 2007
.... ( A ) Whole mount and( B ) section of an embryo electroporated with the control plasmid and hybridized in situ with a Sox10 RNA probe. ( C ) Whole mount and( D ) section of an embryo electroporated with the dominant-negative Spalt4 plasmid and hybridized in situ with a Sox10 RNA probe. ( E ) Embryo 8...
Journal Articles
Journal: Development
Development (2006) 133 (23): 4619–4630.
Published: 1 December 2006
...Thomas J. Carney; Kirsten A. Dutton; Emma Greenhill; Mariana Delfino-Machín; Pascale Dufourcq; Patrick Blader; Robert N. Kelsh sox10 is necessary for development of neural and pigment cell derivatives of the neural crest (NC). However, whereas a direct role for Sox10 activity has been established...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (19): 3817–3826.
Published: 1 October 2006
...Michael O'Donnell; Chang-Soo Hong; Xiao Huang; Raymond J. Delnicki; Jean-Pierre Saint-Jeannet Among the families of transcription factors expressed at the neural plate border, Sox proteins have been shown to regulate multiple aspects of neural crest development. Sox8, Sox9 and Sox10, exhibit...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (10): 2075–2086.
Published: 15 May 2006
...Nadege Bondurand; Dipa Natarajan; Amanda Barlow; Nikhil Thapar; Vassilis Pachnis The transcriptional regulator SOX10 and the signalling molecule endothelin 3 have important roles in the development of the mammalian enteric nervous system (ENS). Using a clonal cell culture system, we show that SOX10...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (5): 941–953.
Published: 1 March 2003
... crest. In addition, the enhancer included another essential element containing conserved binding sites for high mobility group (HMG) box proteins and which responded to factors expressed throughout the neural crest. Consistent with this the NCE was strongly activated in vitro by Sox10, a crest-specific...