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Keywords: siRNA
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Journal Articles
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Reproductive biology
Journal: Development
Development (2016) 143 (17): 3061–3073.
Published: 1 September 2016
...Stephanie Hilz; Andrew J. Modzelewski; Paula E. Cohen; Andrew Grimson MicroRNAs and siRNAs, both of which are AGO-bound small RNAs, are essential for mammalian spermatogenesis. Although their precise germline roles remain largely uncharacterized, recent discoveries suggest that they function...
Journal Articles
Journal: Development
Development (2011) 138 (15): 3093–3102.
Published: 1 August 2011
... of small RNAs to direct transcriptional gene silencing, and we highlight several new findings here. David Baulcombe (University of Cambridge, UK) discussed plant 24-nt siRNAs, which target nascent transcripts and elicit epigenetic modifications of genomic targets. These were implicated in non-cell...
Journal Articles
Journal: Development
Development (2011) 138 (9): 1653–1661.
Published: 1 May 2011
...Nayoung Suh; Robert Blelloch Small non-coding RNAs, including microRNAs (miRNAs), endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), play essential roles in mammalian development. The function and timing of expression of these three classes of small RNAs differ...
Journal Articles
Journal: Development
Development (2006) 133 (15): 2973–2981.
Published: 1 August 2006
... of trans-acting (ta) siRNAs, but is required for the production and/or stability of tasiR-ARF , a ta-siRNA that targets both ETT/ARF3 and ARF4. tasiR-ARF is absent in zip-2 , and overexpression of a tasiR-ARF -insensitive form of ETT mimics the zip phenotype. We conclude that the precocious phenotype...