...Stephanie Hilz; Andrew J. Modzelewski; Paula E. Cohen; Andrew Grimson MicroRNAs and siRNAs, both of which are AGO-bound small RNAs, are essential for mammalian spermatogenesis. Although their precise germline roles remain largely uncharacterized, recent discoveries suggest that they function...

... of small RNAs to direct transcriptional gene silencing, and we highlight several new findings here. David Baulcombe (University of Cambridge, UK) discussed plant 24-nt siRNAs, which target nascent transcripts and elicit epigenetic modifications of genomic targets. These were implicated in non-cell...

...Nayoung Suh; Robert Blelloch Small non-coding RNAs, including microRNAs (miRNAs), endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), play essential roles in mammalian development. The function and timing of expression of these three classes of small RNAs differ...

... of trans-acting (ta) siRNAs, but is required for the production and/or stability of tasiR-ARF , a ta-siRNA that targets both ETT/ARF3 and ARF4. tasiR-ARF is absent in zip-2 , and overexpression of a tasiR-ARF -insensitive form of ETT mimics the zip phenotype. We conclude that the precocious phenotype...