.... Here, we report a novel mechanism by which sex chromosomes cell-autonomously confer sexually different characters upon germ cells prior to gonad formation in a genetically sex-determined species. We have identified a novel gene, Sdgc (sex chromosome-dependent differential expression in germ cells...

... will be presented and reviewed. It will be shown that an autosomal dominant gene mutation with somewhat different phenotypic effects also can cause testicular differentiation in XX individuals. Y chromosome X chromosome autosome sex chromosome sex determination testis-determining factor DNA probe...