... findings indicate that a combination of positive and negative transcriptional inputs program the precise PSC expression of the instructive Hh signal. The GATA factor Serpent (Srp) is essential for hh activation in niche cells, whereas the Suppressor of Hairless [Su(H)] and U-shaped (Ush) transcriptional...

... remain unknown. Here, we show that the highly conserved basic helix-loop-helix (bHLH)transcription factor Hand is expressed in cardioblasts, pericardial nephrocytes and hematopoietic progenitors. The homeodomain protein Tinman and the GATA factors Pannier and Serpent directly activate Hand in these cell...

.... ‡Author for correspondence (e-mail: [email protected] ) 17 4 2001 © 2001. 2001 Drosophila Ecdysone Nuclear receptor GATAb serpent AEF-1 Fbp1 The specific gene transcription patterns formed during development of metazoans result from the activity of the cis...

... for their development. * Author for correspondence (e-mail: [email protected] ) 08 12 1998 04 02 1998 © 1998 by Company of Biologists 1998 Gonadal mesoderm Fat body Drosophila abdominal A Abdominal B clift serpent tinman zinc finger homeodomain protein-1...

... serpent counteracts the effects of these genes and promotes fat body development. The homeotic gene abdominalA limits the region of serpent activity by interfering in a mutually repressive feed back loop between gonadal and fat body development. * Author for correspondence (e-mail: mleptin@uni...

... to this work 22 01 1998 25 11 1997 © 1998 by Company of Biologists 1998 Drosophila Germ cell migration Gonadal mesoderm abdominal A Abdominal B columbus even-skipped fear-of-intimacy fushi-tarazu heartless hedgehog huckebein odd-paired serpent...