...Pia C. Svendsen; Ann Formaz-Preston; Sandra M. Leal; William J. Brook Regional fates in the developing limbs of Drosophila melanogaster are controlled by selector gene transcription factors. Ventral fate in the fly leg is specified by the expression of the ligand Wingless. We present evidence...

... allowed them to act as `selector' genes of sexual information( Mann and Carroll, 2002 ), much as Hox cluster genes specify positional information. Once this crucial function became fixed, upstream regulatory hierarchies could have evolved to allow more complex mechanisms of interpreting the primary sex...

...Myriam Zecca; Gary Struhl Following segregation of the Drosophila wing imaginal disc into dorsal (D) and ventral (V) compartments, the wing primordium is specified by activity of the selector gene vestigial ( vg ). In the accompanying paper, we present evidence that vg expression is itself driven...

...Myriam Zecca; Gary Struhl The Drosophila wing primordium is defined by expression of the selector gene vestigial ( vg ) in a discrete subpopulation of cells within the wing imaginal disc. Following the early segregation of the disc into dorsal (D) and ventral (V) compartments, vg expression...

... downstream of apterous to confer dorsal identity in wing development. §Author for correspondence (e-mail: [email protected] ) 11 6 2001 © 2001. 2001 msh apterous Differentiation Identity Selector gene Drosophila melanogaster Wing Dorsoventral patterning...

...Georg Halder; Sean B. Carroll The formation and identity of organs and appendages are regulated by specific selector genes that encode transcription factors that regulate potentially large sets of target genes. The DNA-binding domains of selector proteins often exhibit relatively low DNA-binding...

... General Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA 18 09 2000 14 12 2000 © 2000 by Company of Biologists 2000 Vertebrate Limb Evolution Development T-box gene Hox gene Pitx1 Selector gene Serial homology Later functional...

... feature of the Drosophila body plan and (2) pnr is the principal gene responsible for this subdivision. We argue that pnr acts like a classical selector gene but differs in that its expression is not propagated through cell divisions. REFERENCES Abu-Shaar , M. , Ryoo , H. D. and Mann , R...

...Marco Milán; Stephen M. Cohen ABSTRACT Dorsoventral axis formation in the Drosophila wing depends on the activity of the selector gene apterous . Although selector genes are usually thought of as binary developmental switches, we find that Apterous activity is negatively regulated during wing...

...Seth S. Blair; Amy Ralston ABSTRACT It is thought that the posterior expression of the ‘selector’ genes engrailed and invected control the subdivision of the growing wing imaginal disc of Drosophila into anterior and posterior lineage compartments. At present, the cellular mechanisms by which...

...Sudipto Roy; K. VijayRaghavan ABSTRACT We have investigated the roles of homeotic selector genes in the migration and fusion of myoblasts, and in the differentiation of adult muscle fibres of Drosophila . Altering intrinsic homeotic identities of myoblasts does not affect their segment-specific...