...Amanda Janesick; Tuyen T. L. Nguyen; Ken-ichi Aisaki; Katsuhide Igarashi; Satoshi Kitajima; Roshantha A. S. Chandraratna; Jun Kanno; Bruce Blumberg Retinoic acid receptor gamma 2 (RARγ2) is the major RAR isoform expressed throughout the caudal axial progenitor domain in vertebrates. During...

... ©2005. 2005 Retinoic acid receptor Retinaldehyde dehydrogenase Periocular mesenchyme Somatic mutagenesis Axenfeld-Rieger's syndrome Vertebrate eye development is a complex process that involves multiple inductive interactions between the forebrain neurectoderm, the ectoderm...

... at interfaces between neural segments called rhombomeres (r). Mechanisms regulating segmental expression have been identified for Hox genes, but for other classes of AP patterning genes there is only limited information. We have analysed the murine retinoic acid receptor β gene ( Rarb ) and show...

... are characterised by a truncation of the anteroposterior axis anterior to the somites, defects in midline mesendodermal tissues and absence of pectoral fins. At a similar anteroposterior level within the nervous system, expression of the retinoic acid receptor α and hoxb4 genes is delayed and significantly reduced...

... of cellular retinoic-acid-binding protein (CRABP). Using order of magnitude calculations, we evaluate how the concentration of CRABP might affect the occupancy state of the retinoic acid receptor. (3) We discuss the spatio-temporal expression pattern of homeobox-containing genes in the developing limb...