... for the activation of Fgf3 expression and the maintenance of Fgf10 and Bmp4 expression in the otic vesicle. Furthermore, loss of Six1 function alters the expression pattern of Nkx5.1 and Gata3 , indicating that Six1 is required for regional specification of the otic vesicle. Finally, our data suggest...

... how the expression of these genes is regulated at the cellular level. In this study, we explored the mechanisms for the differential expression of region-specific transcription factors in neuroepithelial cells by using both primary and immortalized neuroepithelial cells from the rat brain at embryonic...

... in the relative amounts of the different isoforms; for reviews, see Edelman, 1986 ; Rutishauser and Jessell, 1988 ; Goridis et al., 1989 ; Thiery, 1989 ; Walsh and Doherty, 1991 ; Edelman and Crossin, 1991 ; Goridis and Brunet, 1992 ). NCAM mouse neural tube regional specification © 1993...

... ‘cluster’ and the gene complexes of insects strengthen the possibility that, at least in one situation, the problem of regional specification has been solved in a similar way in the two phyla. The embryonic development of the nematode C. elegans has no overt similarity to that of Drosophila...