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Keywords: reelin
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2021) 148 (17): dev199718.
Published: 6 September 2021
...Mohammad I. K. Hamad; Petya Petrova; Solieman Daoud; Obada Rabaya; Abdalrahim Jbara; Nesrine Melliti; Jennifer Leifeld; Igor Jakovčevski; Gebhard Reiss; Joachim Herz; Eckart Förster ABSTRACT Reelin is a large secreted glycoprotein that regulates neuronal migration, lamination and establishment...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (12): dev189936.
Published: 15 June 2020
...Yuki Hirota; Kazunori Nakajima ABSTRACT In the developing neocortex, radially migrating neurons stop migration and form layers beneath the marginal zone (MZ). Reelin plays essential roles in these processes via its receptors, apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (22): 4061–4077.
Published: 15 November 2017
... on the role of the Reelin signaling pathway . Trends Neurosci.   23 , 633 - 638 . 10.1016/S0166-2236(00)01675-1 Barkovich , A. J. , Guerrini , R. , Kuzniecky , R. I. , Jackson , G. D. and Dobyns , W. B. ( 2012 ). A developmental and genetic classification for malformations...
Journal Articles
Journal: Development
Development (2014) 141 (3): 661–673.
Published: 1 February 2014
... and then tangentially, whereas neurons destined for the medial VTA undergo primarily radial migration. We show that tangentially migrating dopaminergic neurons express the components of the reelin signaling pathway, whereas dopaminergic neurons in their initial, radial migration phase express CXC chemokine receptor 4...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (23): 5223–5234.
Published: 1 December 2011
...Jarmila Lakomá; Luis Garcia-Alonso; Juan M. Luque Migration of neurons during cortical development is often assumed to rely on purely post-proliferative reelin signaling. However, Notch signaling, long known to regulate neural precursor formation and maintenance, is required for the effects...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (19): 4315–4326.
Published: 1 October 2011
... about their origin and development. Previous studies suggest that they originate in the medial ganglionic eminence of the telencephalic subpallium; however, our results identified Tbr1 -expressing, reelin-positive neurons migrating from the ventral pallium to the subpallium that differentiate...
Journal Articles
Journal: Development
Development (2008) 135 (12): 2139–2149.
Published: 15 June 2008
... and accumulate below the preplate. The basement membrane is disrupted and radial glial processes are disorganised and lack attachment in C3G-deficient brains. C3G is activated in response to reelin in cortical neurons, which, in turn, leads to activation of the small GTPase Rap1. In C3G-deficient cells, Rap1 GTP...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (21): 3883–3891.
Published: 1 November 2007
...Iris Hack; Sabine Hellwig; Dirk Junghans; Bianka Brunne; Hans H. Bock; Shanting Zhao; Michael Frotscher Reelin, its lipoprotein receptors [very low density lipoprotein receptor(Vldlr) and apolipoprotein E receptor 2 (ApoER2; also known as Lrp8)], and the cytoplasmic adaptor protein disabled 1 (Dab1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (21): 4709–4718.
Published: 1 November 2005
... in the olfactory placode and migrate into the basal forebrain in late embryonic life. Here, we show that reelin, which is expressed along the route of the migrating cells, has an inhibitory role in guiding GnRH neurons to the basal forebrain. Only a small(approximately 5%) subpopulation of these neurons expresses...
Journal Articles
Journal: Development
Development (2004) 131 (20): 5117–5125.
Published: 15 October 2004
...Shanting Zhao; Xuejun Chai; Eckart Förster; Michael Frotscher Reelin is required for the proper positioning of neurons in the cerebral cortex. In the reeler mutant lacking reelin, the granule cells of the dentate gyrus fail to form a regular, densely packed cell layer. Recent evidence suggests...
Journal Articles
Journal: Development
Development (2002) 129 (3): 787–796.
Published: 1 February 2002
...Tara M. Herrick; Jonathan A. Cooper The disabled 1 (Dab1) p80 protein is essential for reelin signaling during brain development. p80 has an N-terminal domain for association with reelin receptors, followed by reelin-dependent tyrosine phosphorylation sites and about 310 C-terminal residues...