... in the dentate gyrus. For the preparation of hippocampal slice cultures, newborn homozygous reeler mouse pups (P0) and young postnatal wild-type mice and rats were used. Brains were removed following decapitation under hypothermic anaesthesia. The hippocampi were dissected and sliced (300 μm...

... not require the neural cell adhesion molecule or the extracellular matrix glycoprotein reelin, as revealed in studies with mutants. However, the pattern of adhesive cues in the reeler mouse hippocampus mimics characteristic alterations of the entorhinal projection in this mutant, suggesting a role of layer...