[email protected] ) 1 These authors contributed equally to the work 26 01 1999 21 03 2000 © 2000 by Company of Biologists 2000 Cranial motor axons Branchial arches Chemoattraction Hepatocyte Growth Factor Rat embryo During neural development, axons navigate...

... nervous system craniofacial development ontogenesis rat embryo That retinoids are essential for normal embryogenesis has been known for over three quarters of a century. Animal feeding trials identified vitamin A (the prohormone retinol) as essential for normal development. Vitamin A deficiency...

... of catecholaminergic properties in sensory neurons. 27 01 1933 © 1993 by Company of Biologists 1993 transmitter phenotype ciliary neurotrophic factor LIF tyrosine hydroxylase sensory ganglia rat embryo Primary sensory neurons exhibit markedly diverse neurochemical properties, including...

... ganglia remain weakly NGFR mRNA-labeled in the posthatch animal. In the rat embryo, NGFR immunoreactivity is present in the auditory placode at E9, in the periotic mesenchyme at E9 –10, and in the medial half of the otocyst at E10 –11. At E12, epithelial NGFR expression becomes restricted anteriorly...

... . 1987 ; Medford et al . 1984 ; Breitbart et al . 1985 ). heart cardiac development cardiac troponin I cDNA slow skeletal troponin I rat embryo © 1991 by Company of Biologists 1991 ...

... staining. Bar: 320 μ m. Fig. 3. Double immunofluorescence staining of muscle fibers from 11-day-old (A and B) and 13.5-day-old (C and D) rat embryos with mAbs RV-C2, specific for cardiac TnT (A and C) and BF-G6, specific for embryonic MHC (B and D). Most of the fibers are labeled by both...

... and Medicine, University of Melbourne, Parkville, Victoria 3052, Australia © 1990 by Company of Biologists 1990 insulin-like growth factors IGF-II receptor rat embryo mannose-6-phosphate mRNA protein Insulin-like growth factors (IGFs) are peptides that have been implicated in embryonic...

... 1989 primary myotubes secondary myotubes insertion myotendinous junction ultrastructure rat embryo In adult skeletal muscles, contractile force exerted by the myofilaments is transmitted to the dense collagenous connective tissue of the tendon (and thence to the skeleton...

...) fibronectin; (D) type-IV collagen. Bar, 20 μ m. * Author for reprints † Recipient of a fellowship from the Association pour la Recherche contre le Cancer 14 10 1987 © 1988 by Company of Biologists 1988 intestine ECM production rat embryo chick embryo...

...S. K. L. Ellington ABSTRACT The glucose metabolism and embryonic development of rat embryos during organogenesis was studied using embryo culture. Glucose uptake and embryonic growth and differentiation of 10·5-day explants (embryos + membranes) were limited by the decreasing glucose concentration...

...J. J. Ross; M. J. Duxson; A. J. Harris ABSTRACT Numbers of myoblasts, primary myotubes and secondary myotubes in developing rat embryo hindlimb IVth lumbrical muscles were counted at daily intervals up until the time of birth, using electron mi-croscopy. Motoneurone death at the spinal cord level...

... ethanol yolk-sac function teratogenesis pinocytosis proteolysis rat embryo Excessive ingestion of ethanol, by either pregnant women or by pregnant experimental animals, is known to induce a characteristic pattern of developmental defects known as the fetal alcohol syndrome ( Abel, 1982...

... Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA 06 10 1986 © 1987 by Company of Biologists 1987 zinc deficiency eye development teratogenesis rat embryo The teratogenicity of zinc deficiency was first demonstrated by Turk and coworkers...

...M.-D. Nagel; J. Nagel ABSTRACT The development of splenic erythroid colony-forming cells from rat embryos in the last 4 days of intrauterine life was examined after 2 and 7 days in a methylcellulose culture system. The number of 2- and 7-day erythroid colonies decreased sharply between...

... – 31 . 10.1002/tera.1420320105 Yonemoto , J. , Brown , N. A. & Webb , M. ( 1984 ). Effects of dimethoxyethyl phthalate, monomethoxyethyl phthalate, 2-methoxyethanol and methoxyacetic acid on postimplantation rat embryos in cultures . Toxicol. Lett . 21 , 97 – 102...

...Gillian M. Morriss-Kay; Fiona Tuckett; Michael Solursh ABSTRACT Day 9 rat embryos (late presomite stage with cranial neural plate or very early neural folds) were cultured for various periods of time from 6–48 h in medium containing 20TRUml -1 Streptomyces hyaluronidase. Exposure to the enzyme...

... at this developmental stage. Copyright © 1986 by Company of Biologists 1986 rat embryo renal isograft ectopic grafts kidney capsule According to the current concept, the initial cell population from which this restriction starts, resides within the embryonic ectoderm of the pregastrulation...

...Martin J. Smedley; Martin Stanisstreet ABSTRACT The role of calcium in neurulation in mammalian embryos has been studied by culturing rat embryos at 10·4 days of gestation, when the cephalic neural folds have elevated but not fused, in serum containing cytoskeletal inhibitors or calcium antagonists...

...Carolyn L. Williams; Paul K. Priscott; I. T. Oliver; George C. T. Yeoh ABSTRACT The uptake of [ 3 H]leucine by the rat yolk sac and embryo and the subsequent synthesis of albumin and transferrin have been studied in whole embryo culture. Rat embryos of 12 days gestation were used in all experiments...

...Martin J. Smedley; Martin Stanisstreet ABSTRACT The role of calcium in neurulation in rat embryos has been studied. Rat embryos at 10-4 days of gestation, when the cephalic neural folds have elevated but not fused, have been cultured in various media, and the effects of these media...