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Keywords: rat
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Journal Articles
Journal: Development
Development (2024) 151 (2): dev202239.
Published: 17 January 2024
... specialized functions. Among the differentiated trophoblast cell lineages are invasive trophoblast cells, which exit the placenta and invade the uterus, where they restructure the uterine parenchyma and facilitate remodeling of uterine spiral arteries. The rat exhibits deep intrauterine trophoblast cell...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2023) 150 (15): dev201826.
Published: 31 July 2023
...Ha T. H. Vu; Regan L. Scott; Khursheed Iqbal; Michael J. Soares; Geetu Tuteja ABSTRACT The invasive trophoblast cell lineages in rat and human share crucial responsibilities in establishing the uterine-placental interface of the hemochorial placenta. These observations have led to the rat becoming...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2023) 150 (13): dev201328.
Published: 12 July 2023
... development and disease. Previously, our group developed methods to produce prostate organoids using induced pluripotent stem cells (iPSCs). Here, we show that human iPSCs can be differentiated into prostate organoids using neonatal rat seminal vesicle mesenchyme in vitro . The organoids can be used to study...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (13): dev201606.
Published: 30 June 2023
... reprogramming is sensitive to the environment, which could impair the establishment of an optimal state of the gamete epigenome, hence proper embryo development. Yet, we lack a comprehensive understanding of DNAme dynamics during spermatogenesis, especially in rats, the model of choice for toxicological studies...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2023) 150 (2): dev201095.
Published: 17 January 2023
... to exit the placenta and invade into the uterus where they restructure the vasculature. Invasive trophoblast cells arise from a well-defined compartment within the placenta, referred to as the junctional zone in rat and the extravillous trophoblast cell column in human. In this study, we investigated...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2020) 147 (4): dev183798.
Published: 21 February 2020
...-gastrulating embryos in mammals, and subsequently migrate towards gonads to mature into functional gametes. Here, we investigated PGC development in rats, by genetically modifying Prdm14 , a unique marker and an essential PGC transcriptional regulator. We trace PGC development in rats, for the first time, from...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (22): 4224–4235.
Published: 15 November 2016
... of GDNF and GFRα1 is required for proper development of hippocampal dendritic arbors and spine maturation through NCAM signaling. GDNF Dendrite complexity Dendritic spines Structural plasticity Hippocampus NCAM Mouse Rat The development of complex, type-specific dendrite morphology...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1560–1570.
Published: 1 May 2016
... induce death of sensory neurons in vitro . The extent to which Sema3A regulates developmental cell death in vivo , however, is debated. We show that in compartmentalized cultures of rat sympathetic neurons, a Sema3A-initiated apoptosis signal is retrogradely transported from axon terminals to cell bodies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (2): 303–313.
Published: 15 January 2015
... experiments using postnatal or adult SVZ progenitors reveal key differences in the connective properties of the neurons generated. Adult neurogenesis Synaptic development Fate determination Subventricular zone Rat New neurons are continuously added to the adult mammalian brain. The most...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (21): 4087–4097.
Published: 1 November 2014
.../nprot.2007.104 Gomes , F. L. A. F. , Zhang , G. , Carbonell , F. , Correa , J. A. , Harris , W. A. , Simons , B. D. and Cayouette , M. ( 2011 ). Reconstruction of rat retinal progenitor cell lineages in vitro reveals a surprising degree of stochasticity in cell fate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (21): 3986–3996.
Published: 1 November 2012
... for correspondence ( tyoung@rics.bwh.harvard.edu ) Competing interests statement The authors declare no competing financial interests. 2 8 2012 © 2012. 2012 Pancortin Olfactomedin Noelin APP Migration Mouse Rat Migration of neuronal precursor cells in the developing cerebral...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (20): 3775–3785.
Published: 15 October 2012
... of Vangl2 expression and shows a strong enrichment of Vangl2 on the SC side. Asterisks indicate Vangl2 enrichment in SCs. D is the same image as in C after 3D deconvolution. ( E-H ′) Surface view projection (Proj XY), single plane view (single XY) and z -stack series (XZ) of the organ of Corti from rat...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (19): 3600–3612.
Published: 1 October 2012
... 2012. Cdh1-APC Smurf1 Axon growth Myelin Ubiquitylation Mouse Rat Axon growth is a crucial process in the developing nervous system. It is controlled by a large number of extrinsic regulatory events, which trigger signaling cascades that involve small GTPase-controlled...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (18): 3306–3315.
Published: 15 September 2012
... ) * These authors contributed equally to this work Competing interests statement The authors declare no competing financial interests. 18 6 2012 © 2012. Astrocyte fate Oligodendroglial differentiation Multiple sclerosis Regeneration Spinal cord injury Rat Cdkn1c...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2010) 137 (14): 2279–2287.
Published: 15 July 2010
...Harry G. Leitch; Kate Blair; William Mansfield; Harold Ayetey; Peter Humphreys; Jennifer Nichols; M. Azim Surani; Austin Smith Mouse and rat embryonic stem cells can be sustained in defined medium by dual inhibition (2i) of the mitogen-activated protein kinase (Erk1/2) cascade and of glycogen...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (3): 415–426.
Published: 1 February 2009
.... These essential steps in oligodendroglial maturation facilitate the detection of target axons, a key step towards myelination. Sprague Dawley rat pups and pregnant BALB/c mice were obtained from Charles River Canada (Montreal, Quebec, Canada). Ntn1 -/+ and Dcc -/+ mice were obtained from Marc Tessier...
Journal Articles
Journal: Development
Development (2008) 135 (17): 2855–2864.
Published: 1 September 2008
... and tissue functions of early embryonic laminins and netrins. Curr. Opin. Cell Biol. 16 , 572 -579. Axon guidance DCC ROCK PRK C3 Y27632 Regeneration Growth cone Rho GTPases Rat During development, axons are directed to their targets along defined pathways by extracellular cues...