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Development (2013) 140 (11): 2377–2386.
Published: 1 June 2013
...Claudio Cantù; Tomas Valenta; George Hausmann; Nathalie Vilain; Michel Aguet; Konrad Basler Pygopus has been discovered as a fundamental Wnt signaling component in Drosophila. The mouse genome encodes two Pygopus homologs, Pygo1 and Pygo2. They serve as context-dependent β-catenin coactivators...
Includes: Supplementary data
Tatyana Y. Belenkaya, Chun Han, Henrietta J. Standley, Xinda Lin, Douglas W. Houston, Janet Heasman, Xinhua Lin
Development (2002) 129 (17): 4089–4101.
Published: 1 September 2002
... family. We report the identification of a new component, Pygopus (Pygo), that plays an essential role in the Wg/Wnt signal transduction pathway. We show that Wg signaling is diminished during embryogenesis and imaginal disc development in the absence of pygo activity. Pygo acts downstream or in parallel...