... J. P. , Hamdoun A. ( 2012 ). Programmed reduction of ABC transporter activity in sea urchin germline progenitors . Development 139 , 783 - 792 . 10.1242/dev.076752 Chen D. , Zheng W. , Lin A. , Uyhazi K. , Zhao H. , Lin H. ( 2012 ). Pumilio 1...

...Lyudmila Y. Kadyrova; Yasuaki Habara; Tammy H. Lee; Robin P. Wharton In the Drosophila embryo, Nanos and Pumilio collaborate to repress the translation of hunchback mRNA in the somatic cytoplasm. Both proteins are also required for repression of maternal Cyclin B mRNA in the germline; it has...

.... † Author for correspondence (e-mail: [email protected] ) * These authors contributed equally to this work 15 6 2006 © 2006. 2006 Caenorhabditis elegans Vulva Pumilio Translational control Signal transduction The spatial and temporal regulation of gene expression...

... involves regulatory molecules that also operate as translational repressors, such as members of PUF proteins. In this study, we identified a homologue of the Drosophila PUF gene Pumilio ( DjPum ) in the planarian Dugesia japonica , with an expression pattern preferentially restricted to neoblasts. Through...

... cycle minibrain pumilio Dictyostelium Nutrient depletion is probably the most common stress that cells encounter and must respond to in order to survive. This is true not only for heterotrophic microorganisms in their natural environment, but also for cells within multicellular animals...

...Alexandria Forbes; Ruth Lehmann ABSTRACT The zinc-finger protein Nanos and the RNA-binding protein Pumilio act together to repress the translation of maternal hunchback RNA in the posterior of the Drosophila embryo, thereby allowing abdomen formation. nanos RNA is localized to the posterior pole...

... activity reduced the polyadenylation status of injected hunchback RNAs by accelerating their deadenylation. Pumilio activity, which is necessary to repress the translation of hunchback , is also needed to alter polyadenylation. An examination of translation indicates a strong correlation between poly...

.... The first, which we refer to as ovarette ( ovt ) mutations, was shown to correspond to a novel class of mutations in the pumilio locus. Since pumilio is known to posttranscriptionally repress the expression of target genes at earlier stages of germ cell development, our results suggest that a similar...

..., pumilio, oskar, valois, vasa, staufen and tudor) into a functional pathway. An activity present in the posterior pole plasm of wild-type embryos can restore normal abdominal development in posterior group mutants. This activity is synthesized during oogenesis and the gene nanos most likely encodes...