... family of vertebrate proto-oncogenes, which synergizes with daughters against dpp and brinker to set the posterior and lateral limits of the region, giving rise to dorsal follicle cells. Moderate Dpp overexpression leads to eggs with enlarged DAs that are shifted towards posterior ( Fig. 3Fa...

... (arrowhead)express Cyclin E periodically. (G-I) dm2 mutant germ cells(arrowhead) also express Dacapo periodically. † Author for correspondence (e-mail: [email protected] ) * These authors contributed equally to this work 20 10 2003 © 2004. 2004 Myc dmyc Proto...

... of neurons. They also strongly suggest that the PAG-3 protein is a DNA-binding protein with properties similar to the mammalian proto-oncogene product GFI-1. * The first two authors contributed equally to this work † Author for correspondence (e-mail: [email protected] ) ‡ Present...

...Daniel Carrasco; Falk Weih; Rodrigo Bravo ABSTRACT We have studied the expression of the c- rel proto-oncogene during mouse embryonic development and adult animals using in situ hybridization and immunocytochemical analysis. c- rel transcripts were detected late in development with an expression...

...Naren R. Ramakrishna; Anthony M. C. Brown ABSTRACT The segment polarity gene wingless is the Drosophila ortholog of mouse Wni-1, a proto-oncogene capable of causing transformation of mammary epithelial cells. These two genes presently represent the best studied members of the Wnt gene family...

...Suzanne L. Mansour; Judy M. Goddard; Mario R. Capecchi ABSTRACT We derived mice that carry a targeted insertion of a neo r gene in the int-2 ( Fgf-3 ) proto-oncogene coding sequences. The mutation was found to be recessive and mice that were homozygous for the insertion did not often survive...

...Lino Tessarollo; Lalitha Nagarajan; Luis F. Parada The c-ros proto-oncogene is the vertebrate homologue of the Drosophila sevenless tyrosine kinase receptor. Examination of c-ros mRNA transcripts in the mouse embryo reveals a stringent pattern of expression. Only kidney, intestine and lung exhibit...

...Katya Manova; Karl Nocka; Peter Besmer; Rosemary F. Bachvarova Recently, it has been shown that the c-kit proto-oncogene is encoded at the white spotting ( W) locus in mice. Mutations of this gene cause depletion of germ cells, some hematopoietic cells and melanocytes. In order to define further...

... , J. M. ( 1985 ). Isolation of the proto-oncogene c-myb from Drosophila melanogaster . Cell 41 , 449 – 456 . 10.1016/S0092-8674(85)80018-0 Kornberg , T. , Siden , I. , O’farrell , P. and Simon , M. ( 1985 ). The engrailed locus of Drosophila’, in situ...

... tyrosine kinase in situ hybridization embryogenesis proto-oncogene An important objective in the field of vertebrate developmental biology is the identification of genes whose products mediate the regulatory signals required for the intricate process of embryogenesis. Various approaches have...

... Laboratory, Postfach 10.2209, 6900 Heidelberg, FRG 19 04 1989 © 1989 by Company of Biologists 1989 proto-oncogene transcription factor c- jun jun B mouse development There is increasing evidence that proto-oncogenes implicated in the control of cell proliferation may also...

... of protein products encoded bv the proto-oncogene int-1. Mol . cell. Biol . 7 . 3971 – 3977 CABRERA. C. V. ALONSO. M. C. JOHNSTON. P. Phillips , R. G. & La Whence , P. A . ( 1987 ). Phenocopies induced with antisense RNA identify the wingless gene . Cell 50 , 658...

... by day 19 of gestation. High levels of fos proto-oncogene expression were, however, retained in the allantoic membranes up to at least day 19 of pregnancy. The expression of the fos protein could be prolonged in trophectodermal cells in monolayer culture by addition of conditioned medium from blastocysts...

...David G. Wilkinson; Sangita Bhatt; Andrew P. Mcmahon The FGF-related proto-oncogene int-2 is implicated in mouse embryogenesis, since it is expressed in specific tissues during gastrulation and neurulation ( Wilkinson et al . 1988 ). Here, we describe the expression of this gene during subsequent...

...Jacques Hourdry; Annie Brulfert; Michel Gusse; Damien Schoevaert; Michael V. Taylor; Marcel Mechali The expression of the proto-oncogene c-myc during oogenesis and embryonic development was followed by in situ hybridization using a cytological protocol adapted to amphibian embryos. The c-myc RNA...

... and growth factors. Little is known, however, about the expression of cellular proto-oncogenes in cells induced to proliferate in vivo by steroid hormones. Experiments reported here indicate that when cells of the immature chicken oviduct are induced to undergo rapid in vivo proliferation by application...