...-mail: [email protected]) 10 05 2000 23 03 2000 © 2000 by Company of Biologists 2000 Preimplantation mouse embryo X chromosome inactivation Chromatin Histone X inactivation involves several changes in the structure or properties of the inactive X chromosome...

... . Development 115 , 1149 – 1164 . Moore , G. P. M. (1975). The RNA polymerase activity of the preimplantation mouse embryo . J. Embryol. Exp. Morph . 34 , 291 – 298 . Moore , G. P. M. and Lintern-Moore , S. (1978). Transcription of the mouse oocyte genome . Biol. Reprod...

... that extracellular t-PA activity is bound to the surface of the fertilized egg. The level of t-PA activity associated with preimplantation mouse embryos decreases in the 2-cell stage embryo, then increases in 4-cell and morula stage embryos. However, morulae grown in culture from fertilized eggs lack t-PA activity...

... undergo discrete modifications at particular points during the cell cycle [ Howlett, 1986 ; Evans et al . 1983 ; Karsenti, 1987]. Detailed work on the early stages of the preimplantation mouse embryo has demonstrated that there are several proteins that are phosphorylated in a cell-cycle-dependent...