... in the embryonic chick. Presumptive hypothalamic cells derive from the rostral diencephalic ventral midline, lie above the prechordal mesendoderm and express Fgf10 . Fgf10 + progenitors undergo anisotropic growth: those displaced rostrally differentiate into anterior cells, then those displaced caudally...

... is essential for specification of dorsoanterior embryonic structures, including notochord, prechordal mesendoderm, floor plate and forebrain. We report that boz mutations disrupt the homeobox gene dharma . Overexpression of boz in the extraembryonic yolk syncytial layer of boz mutant embryos is sufficient...

... is no longer able to induce regions of the nervous system anterior to the hindbrain. Stage 4 + is marked by the emergence from the node of a group of cells, the prechordal mesendoderm. Here we have investigated whether the prechordal region possesses the lost functions of the organizer, using quail-chick...