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Keywords: pointed
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Journal Articles
Journal: Development
Development (2021) 148 (23): dev199465.
Published: 14 December 2021
... midgut constriction defects in Kah mutants similar to those of pointed ( pnt ). ChIP and RNA-Seq data analysis defined a Kah target-binding site similar to that of Snail, and identified a set of common target genes putatively regulated by Kah and Pnt during midgut constriction. Taken together, we report...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (9): dev198796.
Published: 13 May 2021
... downregulation of Pax6 with either the NURF nucleosome remodeling complex or the Pointed transcription factor transforms the head epidermis into an antenna. This is a previously unidentified fate change that is also not observed with the loss of individual genes. We propose that the use of multi-gene knockdowns...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (17): 3109–3118.
Published: 01 September 2016
.... In Drosophila , the Ets protein Pointed P1 (PntP1) is required to generate INPs from type II neuroblasts. Here, we investigated how PntP1 promotes INP generation. By generating pntP1 -specific mutants and using RNAi knockdown, we show that the loss of PntP1 leads to both an increase in type II neuroblast number...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (7): 1170–1181.
Published: 01 April 2016
... positions, and their deployment of ramified arbors to cover specific neuropil territories to form a stereotyped astroglial map. Finally, we unraveled a molecular pathway for astrocyte differentiation in which the Ets protein Pointed and the Notch signaling pathway are required for astrogenesis; however...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (13): 2746–2754.
Published: 01 July 2013
...Arkadi Shwartz; Shaul Yogev; Eyal D. Schejter; Ben-Zion Shilo How signal transduction, which is dynamic and fluctuating by nature, is converted into a stable trancriptional response, is an unanswered question in developmental biology. Two ETS-domain transcription factors encoded by the pointed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (21): 4833–4843.
Published: 01 November 2005
... that this enhancer requires the Egfr/Ras pathway transcription factor Pointed. Recently, others have shown that this same enhancer also requires the eye determining transcription factor Sine oculis(So). We discuss these data in terms of a model for a combinatorial code of furrow movement. dpp:lacZ cn ; ry 506...
Journal Articles
Journal: Development
Development (2004) 131 (8): 1835–1845.
Published: 15 April 2004
..., but not Rhomboid-2 or -4, and the neuregulin-like ligand Vein also function in survival signalling. Pointed mutants display the lowest frequency of fusions, suggesting that EGFR signalling may inhibit apoptosis primarily at the post-translational level. All ventral epidermal cells therefore require some level...
Journal Articles
Journal: Development
Development (2004) 131 (3): 563–570.
Published: 01 February 2004
... activation, but does block nuclear transduction of Egfr activation through transcriptional repression of pointed , which encodes the nuclear effector of the pathway. Thus, Senseless promotes normal R8 differentiation by preventing the effects of autocrine stimulation by Spitz. An analogous relationship...
Journal Articles
Journal: Development
Development (2003) 130 (11): 2419–2428.
Published: 01 June 2003
... propose that REPO plays a key role in both glial development and diversification. * Author for correspondence (e-mail: hidokano@sc.itc.keio.ac.jp ) 10 2 2003 © 2003. 2003 Drosophila Glia Neuron repo tramtrack pointed gcm The two major cell types in the nervous...