...Ha T. H. Vu; Regan L. Scott; Khursheed Iqbal; Michael J. Soares; Geetu Tuteja ABSTRACT The invasive trophoblast cell lineages in rat and human share crucial responsibilities in establishing the uterine-placental interface of the hemochorial placenta. These observations have led to the rat becoming...

...Jenna Treissman; Victor Yuan; Jennet Baltayeva; Hoa T. Le; Barbara Castellana; Wendy P. Robinson; Alexander G. Beristain ABSTRACT Early placental development and the establishment of the invasive trophoblast lineage take place within a low oxygen environment. However, conflicting and inconsistent...

..., suggesting a role in placental development. Here, we evaluate that role. A knock-in reporter for the mouse miR-290 cluster is expressed throughout the embryo until gastrulation, when it becomes specifically expressed in extraembryonic tissues and the germline. In the placenta, expression is limited...

... not caused by failure in cell migration, but rather by abnormal placentation. The β 1D knock-in embryos that survived midgestation developed until birth, but exhibited severely reduced skeletal muscle mass. Quantification of myotube numbers showed that substitution of β 1A with β 1D impairs primary...

... ) 22 01 1998 25 11 1997 © 1998 by Company of Biologists 1998 FGFR2 Chorioallantoic fusion Placentation FGF8 induction Fgf10 expression Limb bud initiation The vertebrate limb bud is an excellent model for studying developmentally related signals (reviewed by Tabin...

... for the extracellular degradation of the uterine matrix. Proteinase activity is controlled by stromal decidualization and specific proteinase inhibitors. This work adds to our understanding of implantation and placentation by reporting the expression and function of another class of proteinases/inhibitors closely...