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Keywords: piRNAs
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Journal Articles
Journal: Development
Development (2018) 145 (17): dev161786.
Published: 7 September 2018
...Patricia Rojas-Ríos; Martine Simonelig ABSTRACT PIWI proteins and Piwi-interacting RNAs (piRNAs) have established and conserved roles in repressing transposable elements (TEs) in the germline of animals. However, in several biological contexts, a large proportion of piRNAs are not related to TE...
Journal Articles
Journal: Development
Development (2014) 141 (18): 3458–3471.
Published: 15 September 2014
...Eva-Maria Weick; Eric A. Miska Distinguishing self from non-self plays a crucial role in safeguarding the germlines of metazoa from mobile DNA elements. Since their discovery less than a decade ago, Piwi-interacting RNAs (piRNAs) have been shown to repress transposable elements in the germline...
Journal Articles
Journal: Development
Development (2013) 140 (18): 3819–3825.
Published: 15 September 2013
... destabilize the genome, an imminent danger during epigenetic reprogramming of cells in the germline. The P-element-induced wimpy testis (PIWI)-interacting RNA (piRNA) pathway is known to silence retrotransposons in the mouse testes. Several piRNA pathway components localize to the unique, germline structure...
Includes: Supplementary data
Journal Articles