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Keywords: piRNA
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Journal Articles
Journal: Development
Development (2023) 150 (4): dev201220.
Published: 16 February 2023
...Thi Thanh My Nguyen; Choijamts Munkhzul; Jeesoo Kim; Yeonju Kyoung; Michele Vianney; Sanghee Shin; Seonmin Ju; Hoang-Anh Pham-Bui; Junhyung Kim; Jong-Seo Kim; Mihye Lee ABSTRACT PIWI-interacting RNAs (piRNAs) are small RNAs that play a conserved role in genome defense. The piRNA processing pathway...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (2): dev193060.
Published: 20 January 2021
... extremely gyrated, displaying general broad opening of chromatin and high levels of intergenic transcription. This is accompanied by changes in nuage morphology, expression of large loci (PGC-expressed non-coding RNA loci, PERLs) that are enriched for retro-transposons and piRNAs, and a rise in piRNA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev195578.
Published: 27 November 2020
... of Biologists Ltd 2020 http://www.biologists.com/user-licence-1-1/ Summary: PLP-1, the C. elegans ortholog of the conserved Pur-alpha proteins, functions downstream of small RNA biogenesis during initiation of gene silencing in the germ line. Pur-alpha puf-8 P granules piRNA Major...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2019) 146 (12): dev171157.
Published: 1 February 2019
...Boris Reznik; Steven A. Cincotta; Rebecca G. Jaszczak; Leslie J. Mateo; Joel Shen; Mei Cao; Laurence Baskin; Ping Ye; Wenfeng An; Diana J. Laird; Allon Klein; Barbara Treutlein ABSTRACT Epigenetic resetting in germ cells during development de-represses transposable elements (TEs). piRNAs protect...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2016) 143 (3): 530–539.
Published: 1 February 2016
...Hui Wang; Zaijun Ma; Kongyan Niu; Yi Xiao; Xiaofen Wu; Chenyu Pan; Yun Zhao; Kai Wang; Yaoyang Zhang; Nan Liu In eukaryotes, aberrant expression of transposable elements (TEs) is detrimental to the host genome. Piwi-interacting RNAs (piRNAs) of ∼23 to 30 nucleotides bound to PIWI clade Argonaute...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (13): 2255–2266.
Published: 1 July 2012
..., Department of Embryology, 3250 San Martin Drive, Baltimore, MD 21218, USA. Competing interests statement The authors declare no competing financial interests. © 2012. Tudor domain RNA metabolism Chromatin piRNA The tudor gene was originally discovered in Drosophila...
Journal Articles
Journal: Development
Development (2011) 138 (15): 3093–3102.
Published: 1 August 2011
... portions of the ovary and focused on functional analysis of Avocado, an MYND-Tudor protein most similar to vertebrate TDRD1. They generated an Avocado mutant, which was sterile and displayed upregulation of transposable elements (TEs) in the germline and soma, owing to a defect in primary piRNA...
Journal Articles
Journal: Development
Development (2009) 136 (6): 965–973.
Published: 15 March 2009
... are born and grow normally but are reproductively infertile. Detailed molecular analyses showed that Sun1 –/– P14 testes are repressed for the expression of reproductive genes and have no detectable piRNA. These findings raise a heretofore unrecognized role of Sun1 in the selective gene expression...
Includes: Supplementary data