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Keywords: par-3
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Journal Articles
Journal: Development
Development (2019) 146 (6): dev171116.
Published: 25 March 2019
... to the posterior cytoplasm of C. elegans zygotes. Polarity Kinase PAR proteins MEX-6 P granules PAR-3 Cell polarity is central to many cellular and developmental processes, such as axon specification, cell migration, tissue morphogenesis and asymmetric cell division. The kinase PAR-1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (6): dev171116.
Published: 25 March 2019
... to the posterior cytoplasm of C. elegans zygotes. Polarity Kinase PAR proteins MEX-6 P granules PAR-3 National Institutes of Health 10.13039/100000002 R37HD037047 F32GM117814 Howard Hughes Medical Institute 10.13039/100000011 Cell polarity is central to many...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (22): 5339–5350.
Published: 15 November 2003
..., such as PAR-3 and PAR-6, redistribute to the outer, apical surfaces of cells, whereas posteriorly localized PAR proteins, such as PAR-1 and PAR-2, redistribute to the inner, basolateral surfaces. Because PAR proteins are provided maternally, distinguishing apicobasal from earlier anterior-posterior functions...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (2): 387–397.
Published: 15 January 2002
...Jeremy Nance; James R. Priess Gastrulation in C. elegans embryos involves formation of a blastocoel and the ingression of surface cells into the blastocoel. Mutations in the par-3 gene cause abnormal separations between embryonic cells, suggesting that the PAR-3 protein has a role in blastocoel...
Journal Articles
Journal Articles
Journal: Development
Development (1997) 124 (19): 3815–3826.
Published: 1 October 1997
... par-1 par-2 par-3 par-4 skn-1 The generation of asymmetry before mitosis is a general mechanism for producing cells with different fates during growth and development (for a review, see Gonczy and Hyman, 1996 ). For example, sperm entry provides an extrinsic cue to polarize the 1...
Journal Articles
Journal: Development
Development (1996) 122 (10): 3075–3084.
Published: 1 October 1996
... in embryos is very similar to that of PAR-1 protein. By analyzing the distribution of the PAR-2 protein in various par mutant backgrounds we found that proper asymmetric distribution of PAR-2 depends upon par-3 activity but not upon par-1 or par-4. par-2 activity is required for proper cortical localization...