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Keywords: par-2
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Journal Articles
Journal: Development
Development (2010) 137 (10): 1669–1677.
Published: 15 May 2010
..., we demonstrate the existence of a second, parallel and redundant pathway that can polarize the zygote in the absence of ECT-2-dependent cortical flows. This second pathway depends on the polarity protein PAR-2. We show that PAR-2 localizes to the cortex nearest the sperm centrosome even...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (15): 3513–3525.
Published: 1 August 2004
... cell division. Independently of its role in meiotic progression, CUL-2 is required to limit the initiation/spread of the polarity protein PAR-2 in regions distant from microtubule organizing centers. Finally,we show that inactivation of the leucine-rich repeat protein ZYG-11 produces meiotic...
Journal Articles
Journal: Development
Development (2002) 129 (2): 387–397.
Published: 15 January 2002
... Apical-basal polarity Gastrulation Ingression Morphogenesis Cell fate Cell shape Non-muscle myosin LIT-1 HMR-1 NMY-2 PAR-2 PAR-3 PAR-6 C. elegans Numerous studies on C. elegans embryos have revealed the basic strategies that establish the anterior-posterior and dorsal-ventral...
Journal Articles
Journal: Development
Development (1997) 124 (19): 3815–3826.
Published: 1 October 1997
... par-1 par-2 par-3 par-4 skn-1 The generation of asymmetry before mitosis is a general mechanism for producing cells with different fates during growth and development (for a review, see Gonczy and Hyman, 1996 ). For example, sperm entry provides an extrinsic cue to polarize the 1...
Journal Articles