...Paul Z. Liu; Thomas C. Kaufman The pair-rule gene even-skipped is required for the initiation of metameric pattern in Drosophila . But Drosophila segmentation is evolutionarily derived and is not representative of most insects. Therefore, in order to shed light on the evolution of insect...

...Simon L. Bullock; Michael Stauber; Alexander Prell; Julian R. Hughes; David Ish-Horowicz; Urs Schmidt-Ott Establishment of segmental pattern in the Drosophila syncytial blastoderm embryo depends on pair-rule transcriptional regulators. mRNA transcripts of pair-rule genes localise to the apical...

..., but the evolutionary origin of the mechanism, the pair-rule system, is unclear. We have examined the expression of the homologues of two Drosophila pair-rule genes, runt and paired (Pax Group III), in segmenting embryos of the two-spotted spider mite (Tetranychus urticae Koch). Spider mites are chelicerates, a group...

...Gregory K. Davis; Carlos A. Jaramillo; Nipam H. Patel Pair-rule genes were identified and named for their role in segmentation in embryos of the long germ insect Drosophila . Among short germ insects these genes exhibit variable expression patterns during segmentation and thus are likely to play...

... of these gene products, the protein encoded by the pair-rule gene odd-skipped (Odd) is a DNA-binding transcription factor. Genetic experiments have suggested several candidate target genes for Odd, all of which appear to be negatively regulated. Here we use pulses of ectopic Odd expression to test the response...

... to the dominant wing mutation Dichaete . Homozygous deletions of the Sox70D gene and recessive lethal Dichaete alleles have a variable embryonic segmentation phenotype. Dichaete is expressed in early embryos in a dynamic pattern reminiscent of gap and pair-rule genes and is required for the appropriate expression...

... a screen for mutations that alter embryonic patterning of the beetle, Tribolium castaneum . One of the mutations isolated, godzilla , affects early steps in the segmentation process in the whole animal, like Drosophila pair-rule mutants. Another mutation, jaws , is novel: it causes both a dramatic homeotic...

...James A. Langeland; Sherwin F. Attai; Kathy Vorwerk; Sean B. Carroll ABSTRACT We present a genetic and molecular analysis of two hairy (h) pair-rule stripes in order to determine how gradients of gap proteins position adjacent stripes of gene expression in the posterior of Drosophila embryos. We...

... in stripes at the blastoderm stage, h is also expressed later in the stomodæum, proctodæum, tracheal pits and mesoderm. We demonstrate that h protein stripes show consistent phase relationships to those of the even-skipped (eve) pair-rule gene. We examine h protein patterns in embryos mutant for other...