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Keywords: p48
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Journal Articles
Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas
Available to PurchaseFarzad Esni, Bidyut Ghosh, Andrew V. Biankin, John W. Lin, Megan A. Albert, Xiaobing Yu, Raymond J. MacDonald, Curt I. Civin, Francisco X. Real, Michael A. Pack, Douglas W. Ball, Steven D. Leach
Journal:
Development
Development (2004) 131 (17): 4213–4224.
Published: 1 September 2004
... subsequent exocrine differentiation events. Here, we show that activated Notch and Notch target genes actively repress completion of an acinar cell differentiation program in developing mouse and zebrafish pancreas. In developing mouse pancreas, the Notch target gene Hes1 is co-expressed with Ptf1-P48...
Includes: Supplementary data