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1-7 of 7
Keywords: p27Kip1
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Journal Articles
Journal:
Development
Development (2008) 135 (4): 729–741.
Published: 15 February 2008
... at E10.5 (arrows). (C-K) Immunostaining of E11.5 spinal cords demonstrating overlapping activity of Cux2 (green) and P27Kip1 (red) in the rp, vz and a 2-4-cell-layer-thick region outlining the iz (arrowhead) as well as the fp. Scale bar: 500 μm in C. We initially characterized the activity...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2006) 133 (15): 2817–2826.
Published: 1 August 2006
.... † Author for correspondence (e-mail: [email protected]) * These authors contributed equally to this work 9 5 2006 © 2006. 2006 p27Kip1 Cell cycle Development Morphogenesis Inner ear Cochlea Organ of Corti Mouse Cell proliferation and differentiation are coordinated...
Journal Articles
Genetic rescue of cell number in a mouse model of microphthalmia:interactions between Chx10 and G1-phase cell cycle regulators
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Journal:
Development
Development (2003) 130 (3): 539–552.
Published: 1 February 2003
... -297. Chen, P. and Segil, N. (1999). p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti. Development 126 , 1581 -1590. Cheng, M., Sexl, V., Sherr, C. J. and Roussel, M. F. (1998). Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated...
Journal Articles
The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination
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Journal:
Development
Development (2002) 129 (10): 2495–2505.
Published: 15 May 2002
... primordium in the cochlea is marked by p27Kip1 and the zone of non-proliferating cells (ZNPC). Timed-mated pregnant animals were injected with BrdU at E12.5 (A,B), E13.5 (C,D) and E14.5 (E,F), and sacrificed 8 hours later. Adjacent sections from each stage were stained with antibody to either BrdU (A,C,E...
Journal Articles
Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors
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Journal:
Development
Development (2002) 129 (2): 455–466.
Published: 15 January 2002
... and mutant cells at all time-points from 12.75 hours after plating. Regression analysis showed that the rate of increase for the mutant cells was just over twice that for the wild-type cells (r2=0.88 for Pax6Sey/Sey and 0.99 for wild type). (C,D) Percentages of cells expressing cyclin A (C) and p27kip1 (D...
Journal Articles
Loss of p27Kip1 function results in increased proliferative capacity of oligodendrocyte progenitors but unaltered timing of differentiation
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Journal:
Development
Development (1999) 126 (18): 4027–4037.
Published: 15 September 1999
... the number of cell divisions to growth arrest and differentiation. A direct prediction of this model is that an increase in the number of cell divisions would result in a delayed onset of differentiation. Since the cell cycle inhibitor p27Kip1 is an essential component of the machinery leading...
Journal Articles
p27 Kip1 links cell proliferation to morphogenesis in the developing organ of Corti
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Journal:
Development
Development (1999) 126 (8): 1581–1590.
Published: 15 April 1999
... Durand , B. , Fero , M. L. , Roberts , J. M. and Raff , M. C. (1998). p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation . Curr. Biology 8 , 431 – 440 . 10.1016/S0960-9822(98)70177-0...