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Keywords: osteogenesis
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Journal Articles
Journal: Development
Development (2021) 148 (23): dev199607.
Published: 2 December 2021
... demonstrates alterations in osteogenic and chondrogenic precursors caused by PDGFRβ D849V . Mutant cells undergo poor osteogenesis in vitro with increased expression of Sox9 and other chondrogenic markers. Mice with PDGFRβ D849V exhibit osteopenia. Increased STAT5 phosphorylation and overexpression of Igf1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 334–344.
Published: 15 January 2017
... of NPs, no other peptide hormones that affect remote organs have been identified from the heart. We identified osteocrin (Ostn) as an osteogenesis/chondrogenesis regulatory hormone secreted from CMs in zebrafish. ostn mutant larvae exhibit impaired membranous and chondral bone formation. The impaired...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 265–271.
Published: 15 January 2017
... bone defects and larval lethality, establishing a key role for Osterix in bone formation in a non-mammalian species. Osteoblasts Osteogenesis Bone modelling Skeleton Medaka Osteoblasts are bone matrix-forming cells that differentiate from Sox9 - and Runx2 -positive mesenchymal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (4): 867–877.
Published: 15 February 2014
... interests The authors declare no competing financial interests. 18 1 2013 20 11 2013 © 2014. Published by The Company of Biologists Ltd 2014 Ezh2 Epigenetic regulation Neural crest Chondrogenesis Osteogenesis Mouse Neural crest cells (NCCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (2): 203–213.
Published: 15 January 2011
... development and remodeling in the adult, and regulates osteogenesis in a cell-autonomous and non-autonomous manner. * Author for correspondence ( sylvie.hardouin@cea.fr ) Author contributions S.N.H. conceived the project, designed, performed and interpreted the experiments, and wrote the paper...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (22): 3765–3774.
Published: 15 November 2008
... is completely phenocopied by treating 4 dpf wild-type embryos with either RA or the pharmacological Cyp26 blocker R115866, thus identifying a previously unappreciated role for RA and cyp26b1 in osteogenesis of the vertebral column. Cyp26b1 is expressed within osteoblast cells,demonstrating that RA levels within...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (11): 2143–2152.
Published: 1 June 2001
... ). If a comparable downregulation occurs in neural crest cells grown in the absence of FGF2 during the initial crucial period of culture, then the ability to respond to FGF at later times in culture might be absent or reduced. Neural crest Culture FGF2 FGFR Chondrogenesis Osteogenesis Skull Quail...
Journal Articles
Journal: Development
Development (1986) 92 (1): 133–143.
Published: 1 March 1986
... and osteogenesis in the os penis and the erectile tissue formation in the corpus cavernosum penis of rats are dependent on androgens, while the rudiments of these tissues can be formed without androgens (Murakami, in preparation). * Present address: Biological Institute, Faculty of Science, Yamaguchi University...