... to progress normally from the optic chiasm into the optic tracts. The underlying cause is unknown but, in principle, can result from either the disruption of guidance mechanisms that mediate axon exit from the midline chiasm region or defects in growth cone signaling required for entry into the lateral...

... 1995 © 1995 by Company of Biologists 1995 polysialic acid optic axons visual system development axon fasciculation axon guidance mechanism optic tectum optic tract chick The polysialic acid moiety (PSA) attached to the neural cell adhesion molecule (NCAM), has strong anti...

... is gradually refined into an accurate retinotectal map by a process that depends on afferent activity. On their way to the tectum, many regenerating axons make erroneous choices between the two arms (brachia) of the optic tract. However, since they commonly possess divergent collateral branches, a secondary...

...David L. Becker; Jeremy E. Cook ABSTRACT In the normal goldfish, optic axons are distributed between the two arms (brachia) of each optic tract, in such a way that each axon enters the tectum close to its retinotopic termination site. We have shown previously that regenerating axons at first...

...David L. Becker; Jeremy E. Cook ABSTRACT The optic tract of the goldfish splits into two brachia just before it reaches the tectum, normal optic axons being distributed systematically between the two according to their retinal origins. The orderliness of this division, like that of the retinotectal...