... for anteroposterior and columnar genes for dorsoventral patterning. In this report, we analyse the role of the columnar patterning gene ventral nervous system defective ( vnd ) in embryonic brain development. Expression of vnd is observed in specific subsets of cells in all brain neuromeres. Loss-of-function analysis...

...Luc Mathis; Johan Sieur; Octavian Voiculescu; Patrick Charnay; Jean-François Nicolas ABSTRACT We made use of the laacz procedure of single-cell labelling to visualize clones labelled before neuromere formation, in 12.5-day mouse embryos. This allowed us to deduce two successive phases of cell...

... regional specification neural stem cells neuromere homeobox gene rat The mammalian central nervous system is the center of higher cognitive functions. Its generation involves a number of events including neural induction, patterning of the neural plate, commitment and differentiation of neurons...

..., neuropore; OV, otic vesicle; PNA, peanut agglutinin; P, prosencephalon; Rl, rhombomere No. 1; R, rhombencephalon; T, telencephalon. brain segmentation cerebellum cranial nerves mesoderm rhombomere neuromere otic vesicle ’ … deswegen ich denn auch nur kürzlich meine vieljahrig gehegte...

... that are derived from head mesoderm in addition to other sources. Two major regions of the central nervous system, the spinal cord and hindbrain, are also segmentally organized, as deduced from the distribution of identified neurones in both regions and by formation of neuromeres in the hindbrain that contain...

... to the length of a somite. In the hindbrain, a series of neuromeres of corresponding length is present, and the earliest neurones are located in the centres of each neuromere. Young neurones within both the hindbrain and spinal cord were identified in live embryos using Nomarski optics, and histochemically...