... that the myriapod pattern of neural precursor formation is compatible with the possibility of a chelicerate-myriapod sister group relationship. * Author for correspondence (e-mail: [email protected] ) 18 2 2003 © 2003. 2003 Proneural genes Neurogenic genes Neurogenesis...

... of sensory neurons. †Author for correspondence (e-mail: [email protected] ) 8 3 2002 © 2002. 2002 Neural crest Zebrafish Delta/Notch signaling Rohon-Beard neuron bHLH Neurogenin Proneural genes Neurogenic genes Although the molecular machinery that regulates...

...-cell interactions, mediated by zebrafish homologues of the Drosophila melanogaster neurogenic gene, Delta , regulate specification of diverse neuronal types in the ventral spinal cord. We describe identification of a novel zebrafish Delta gene expressed specifically in the nervous system and show...

... and ligands in the Notch signaling pathway are generated by different induction mechanisms. * Author for correspondence (e-mail: [email protected] ) 06 02 1997 © 1997 by Company of Biologists 1997 Notch Serrate-1 neurogenic genes tooth embryonic development tissue...

... RBP-J к /KBF2/CBF1 neurogenic genes ESR-1 transcriptional activation Enhancer of split The main finding of our studies is that X-Su(H)1 is required for Notch signaling in vivo, where the number of neurons that form during primary neurogenesis appears to be regulated by lateral...

... of the Drosophila neurogenic gene Notch and its pattern of transcription during early embryogenesis . Mech. Dev . 43 , 87 – 100 . 10.1016/0925-4773(93)90027-U Blagoeva , P. and Stoichev , I. ( 1979 ). In vivo inhibition of the tyrosinase of hamster melanoma with sodium...

...Scott Goode; Michael Melnick; Tze-Bin Chou; Norbert Perrimon ABSTRACT Notch ( N ) and other neurogenic genes have been implicated in two fundamental processes, lateral specification of cell fates, and epithelial development. Previous studies have suggested that the neurogenic gene brainiac ( brn...

... in very different spatial patterns. We show that the pattern of primary neurons induced by XASH-3 and NeuroD can be accounted for by a difference in their sensitivity to inhibitory interactions mediated by the neurogenic genes, X-Delta-1 and X-Notch-1 . Both NeuroD and XASH-3 promote the expression...

... potential as visualized by the expression of the proneural genes achaete and scute . A class of genes, known as the ‘neurogenic genes’, function to restrict the proportion of cells that differentiate as sensory organ precursors. They mediate cell communication between the competent cells by means...

... and requires proneural and neurogenic genes. In neurogenic mutants the principle midgut epithelial cells are missing and the other two cell types develop in great excess. Consequently, the midgut epithelium does not form. In achaete-scute complex and daughterless mutants the interstitial cell precursors do...

... is antagonized by neurogenic genes, resulting in the realization of the neural potential in a single cell per cluster. To analyse the relationship between proneural and neurogenic genes, we have studied, in specific proneural clusters and neuroblasts of wild-type and neurogenic mutants embryos, the expression...

... genes and the selection of a single cell from each group involves lateral inhibition, mediated by the neurogenic genes. We confirm the mitogenic role of the tip cell during embryogenesis by mutational analysis and show that it subsequently adopts a second fate, differentiating neural characteristics. We...

... scabrous neurogenic genes extracellular matrix The development of the adult peripheral nervous system (PNS) of Drosophila is initiated in the third larval instar when regions within each imaginal disc are defined that will give rise to sensory organ precursors. Subsequently, within each...

... of Hairless; Hairless double mutant imaginal discs, suggest that the two genes act antagonistically to commit imaginal disc cells stably to alternative fates. 15 03 1994 © 1994 by Company of Biologists 1994 Hairless Suppressor of Hairless neurogenic genes asymmetric cell division...

... that stay behind as epidermal precursors ( Lehmann et al., 1983 ). Thus, embryos lacking the function of any of the neurogenic genes show an increased number of delaminating neuroblasts, at the expense of epi- dermal precursors. The neurogenic genes Notch ( N ), big brain ( bib ) and Delta ( Dl...

... guided by two opposing classes of genes. The proneural genes, including the members of the achaete-scute complex (AS-C), promote neurogenesis, while the neurogenic genes prevent neurogenesis and facilitate epidermal development. To understand the role that proneural gene expression and regulation play...